Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Neurology, Jefferson Comprehensive Epilepsy Center, Thomas Jefferson University, Philadelphia, PA, USA.
Acta Neurol Scand. 2020 Oct;142(4):392-395. doi: 10.1111/ane.13310. Epub 2020 Jul 22.
To investigate the effects of COVID-19 pandemic on patients' perceptions of hardship in obtaining their drugs and if this pandemic and the social restrictions in response to that has resulted in any changes in their seizure control status. We also investigated factors potentially associated with the perceptions of difficulty in obtaining their drugs (eg, polytherapy vs monotherapy, taking imported drugs, and seizure status worsening).
We surveyed a random sample of patients with epilepsy, who were registered in our database at Shiraz Epilepsy Center, Iran, on their perceptions on two issues: (a) What has been your experience on obtaining your antiseizure medications in the past 4 weeks (compared to before)? (b) Have you experienced any changes in your seizure control status in the past 4 weeks?
We included 100 patients (53 male and 47 female patients). In response to the question "Have you had any difficulties in the past 4 weeks to obtain your drugs?," 31 people (31%) expressed hardship obtaining their drugs. In response to the question "How has been your seizure control status compared with before?," six people (6%) expressed worsening of their seizure control status in the past 4 weeks. None of the patients reported symptoms of coronavirus infection.
About one-third of patients with epilepsy expressed significant hardship obtaining their drugs after the intensification of the COVID-19 outbreak in Iran. The current COVID-19 pandemic could be considered as a major shock to a nation that has already been under significant pressure (ie, Iran).
研究 COVID-19 大流行对患者获取药物困难程度的影响,以及这种大流行和为应对这种大流行而实施的社会限制是否导致其癫痫发作控制状况发生任何变化。我们还研究了可能与获取药物的困难程度有关的因素(例如,多药治疗与单药治疗、服用进口药物以及癫痫发作状况恶化)。
我们对伊朗设拉子癫痫中心数据库中登记的随机抽取的癫痫患者进行了调查,调查了他们对两个问题的看法:(a)在过去的 4 周内,您在获得抗癫痫药物方面有何经验(与之前相比)?(b)在过去的 4 周内,您的癫痫发作控制状况是否发生了任何变化?
我们共纳入了 100 名患者(53 名男性和 47 名女性患者)。在回答“在过去的 4 周内,您在获得药物方面是否遇到任何困难?”这一问题时,有 31 人(31%)表示在获取药物方面存在困难。在回答“与之前相比,您的癫痫发作控制状况如何?”这一问题时,有 6 人(6%)表示在过去的 4 周内癫痫发作控制状况恶化。没有患者报告出现冠状病毒感染的症状。
大约三分之一的癫痫患者在伊朗 COVID-19 疫情加剧后表示在获取药物方面存在重大困难。目前的 COVID-19 大流行可能被视为一个已经面临巨大压力的国家(即伊朗)的重大冲击。