Department of Biology, College of Arts and Sciences, Georgia State University, Atlanta, GA, USA.
Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Centre, Omaha, NE, USA; Department of Genetics, Cell Biology and Anatomy, Omaha, NE, USA; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Centre, Omaha, NE, USA.
J Autoimmun. 2020 May;109:102433. doi: 10.1016/j.jaut.2020.102433. Epub 2020 Feb 26.
Coronavirus disease (COVID-19) is caused by SARS-COV2 and represents the causative agent of a potentially fatal disease that is of great global public health concern. Based on the large number of infected people that were exposed to the wet animal market in Wuhan City, China, it is suggested that this is likely the zoonotic origin of COVID-19. Person-to-person transmission of COVID-19 infection led to the isolation of patients that were subsequently administered a variety of treatments. Extensive measures to reduce person-to-person transmission of COVID-19 have been implemented to control the current outbreak. Special attention and efforts to protect or reduce transmission should be applied in susceptible populations including children, health care providers, and elderly people. In this review, we highlights the symptoms, epidemiology, transmission, pathogenesis, phylogenetic analysis and future directions to control the spread of this fatal disease.
冠状病毒病（COVID-19）由 SARS-COV2 引起，是一种可能致命的疾病的病原体，对全球公共卫生构成极大威胁。鉴于大量感染者曾接触过中国武汉市的潮湿动物市场，COVID-19 很可能源自该动物市场的动物。人与人之间的 COVID-19 感染传播导致患者被隔离，并随后接受了各种治疗。为控制当前疫情，已采取广泛措施减少人与人之间的 COVID-19 传播。应特别关注和努力保护或减少在易感人群（包括儿童、医护人员和老年人）中的传播。在本综述中，我们重点介绍了该致命疾病的症状、流行病学、传播、发病机制、系统发育分析和未来控制传播的方向。
Zotero 插件