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内镜第三脑室造瘘术治疗特发性颅内高压:病例报告及文献复习。

The Use of Endoscopic Third Ventriculostomy as Treatment for Idiopathic Intracranial Hypertension: Case Report and a Review of Previously Reported Cases.

机构信息

University of Miami Miller School of Medicine, Miami, Florida, USA.

University of Miami Miller School of Medicine, Miami, Florida, USA.

出版信息

World Neurosurg. 2020 Sep;141:373-376. doi: 10.1016/j.wneu.2020.06.088. Epub 2020 Jul 4.

Abstract

BACKGROUND

Idiopathic intracranial hypertension (IIH), or pseudotumor cerebri, is a rare disorder marked by an increase of cerebrospinal fluid pressure that may cause severe headaches, papilledema, vision loss, and other symptoms. IIH is typically treated with shunts, but shunts are prone to malfunction and infection, resulting in many patients experiencing recurrent headaches after treatment.

CASE DESCRIPTION

A 41-year-old woman with IIH presented with a history of severe headaches and seizures with documented elevated intracranial pressure (opening pressure 250 mm HO). After failure of several medical treatments, the patient was offered surgery for symptomatic relief. Given the patient's ventricular anatomy and preference, IIH was treated with endoscopic third ventriculostomy rather than a conventional shunt.

CONCLUSIONS

Reported resolution of the patient's headaches and improved quality of life following the procedure indicated that endoscopic third ventriculostomy can be used to treat IIH if ventricles are not completely slitlike. Additionally, we present a review of all previously reported cases in which endoscopic third ventriculostomy was used for the treatment of IIH.

摘要

背景

特发性颅内高压(IIH),也称假性脑瘤,是一种罕见的疾病,其特征是脑脊液压力升高,可能导致严重头痛、视乳头水肿、视力丧失和其他症状。IIH 的典型治疗方法是分流术,但分流术容易发生故障和感染,导致许多患者在治疗后反复出现头痛。

病例描述

一名 41 岁女性患有 IIH,有严重头痛和癫痫病史,记录的颅内压升高(开放压力 250mmHO)。在几种药物治疗失败后,患者因症状缓解而接受手术。鉴于患者的脑室解剖结构和偏好,采用内镜下第三脑室造瘘术而不是传统的分流术来治疗 IIH。

结论

该患者的头痛缓解和生活质量提高表明,在脑室不完全呈裂隙样的情况下,内镜下第三脑室造瘘术可用于治疗 IIH。此外,我们还回顾了所有先前报道的使用内镜下第三脑室造瘘术治疗 IIH 的病例。

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