Department of Thoracic Surgery, Dr Suat Seren Chest Diseases and Surgery Medical Practice Research Center, University of Health Sciences, Izmir, Turkey.
Thorac Cardiovasc Surg. 2021 Mar;69(2):189-193. doi: 10.1055/s-0040-1713138. Epub 2020 Jul 7.
Video-assisted mediastinoscopy (VAM) is a valuable method in the investigation of diseases with mediastinal lymphadenopathy or those localized in the mediastinum. The aim of this study was to determine the diagnostic value of VAM in the investigation of mediastinal involvement of nonlung cancer diseases and to describe our institutional surgical experience.
Clinical parameters such as age, sex, histological diagnosis, morbidity, and mortality of all patients who underwent VAM for the investigation of mediastinal involvement of diseases except lung cancer between January 2006 and July 2018 were retrospectively reviewed, and the diagnostic efficacy of VAM was determined statistically.
During the study period, 388 patients underwent VAM, and 536 lymph nodes were sampled for histopathological evaluation of mediastinum due to mediastinal lymphadenopathy or paratracheal lesions. The most common diagnoses were sarcoidosis ( = 178 [45.9%]), tuberculous lymphadenitis ( = 108 [27.8%]), lymphadenitis with anthracosis ( = 72 [18.6%]), and lymphoma ( = 15 [3.9%]).
The results of the study show that VAM should be used because of its high diagnostic benefit in mediastinal lymphadenopathies, which are difficult to diagnose, or mediastinal lesions located in the paratracheal region. Despite the increase in the number of new diagnostic modalities, VAM is still the most effective method and a gold standard.
电视辅助纵隔镜检查（VAM）是一种用于诊断纵隔淋巴结病或纵隔内局限性疾病的有价值的方法。本研究旨在确定 VAM 在非肺癌疾病纵隔受累调查中的诊断价值，并描述我们机构的手术经验。
回顾性分析 2006 年 1 月至 2018 年 7 月期间，所有因纵隔淋巴结病或气管旁病变接受 VAM 检查的患者的临床参数，如年龄、性别、组织学诊断、发病率和死亡率，并统计 VAM 的诊断效果。
在研究期间，388 例患者接受了 VAM 检查，536 个淋巴结被取样进行纵隔组织病理学评估，原因是纵隔淋巴结病或气管旁病变。最常见的诊断是结节病（ = 178 [45.9%]）、结核性淋巴结炎（ = 108 [27.8%]）、含炭末性淋巴结炎（ = 72 [18.6%]）和淋巴瘤（ = 15 [3.9%]）。
研究结果表明，对于难以诊断的纵隔淋巴结病或位于气管旁区域的纵隔病变，VAM 因其高诊断获益而应被采用。尽管新的诊断方法数量有所增加，但 VAM 仍然是最有效的方法和金标准。
