Felber S, Rosenthal P, Henton D
Division of Digestive Diseases and Nutrition, Children's Hospital of Los Angeles, CA 90027.
J Pediatr Gastroenterol Nutr. 1988 Sep-Oct;7(5):685-7. doi: 10.1097/00005176-198809000-00011.
Localizing the bleeding site in pediatric patients with gastrointestinal hemorrhage may require invasive and costly diagnostic procedures. A simple index to discriminate upper and lower bleeding sources would be invaluable. We evaluated the reliability of the calculated blood urea nitrogen/creatinine (BUN/Cr) ratio in segregating upper from lower gastrointestinal bleeding sites in 40 children. For upper gastrointestinal hemorrhage, the calculated BUN/Cr ratios (mg/mg) ranged from 10 to 140, with a mean value of 34. For lower gastrointestinal bleeders, the BUN/Cr ratios ranged from 3.3 to 30, with a mean value of 16. All BUN/Cr ratios greater than 30 corresponded to patients with documented upper gastrointestinal bleeding sources. Calculation of the BUN/Cr ratio in the initial evaluation of gastrointestinal bleeding may prove useful in guiding the sequence of diagnostic procedures and examinations.
定位小儿胃肠道出血的出血部位可能需要侵入性且昂贵的诊断程序。一个用于区分上消化道和下消化道出血来源的简单指标将非常有价值。我们评估了计算得出的血尿素氮/肌酐（BUN/Cr）比值在区分40名儿童上、下消化道出血部位方面的可靠性。对于上消化道出血，计算得出的BUN/Cr比值（mg/mg）范围为10至140，平均值为34。对于下消化道出血患者，BUN/Cr比值范围为3.3至30，平均值为16。所有大于30的BUN/Cr比值均对应有记录的上消化道出血来源的患者。在胃肠道出血的初始评估中计算BUN/Cr比值可能有助于指导诊断程序和检查的顺序。
