Khan Sovann, Choi Yunseok, Ahn Hak-Young, Han Jae Hyun, Ju Byeong-Kwon, Chung Jaewon, Cho So-Hye
Photocatalysis International Research Center, Tokyo University of Science, 2641 Yamazaki, Noda-shi, Chiba 278-8510, Japan.
Materials Architecturing Research Center, Korea Institute of Science & Technology, 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Korea.
Materials (Basel). 2020 Jul 4;13(13):2987. doi: 10.3390/ma13132987.
Recently, the use of oxide-based nanomaterials for bio-imaging has received great attention owing to their remarkable stabilities as compared to those of conventional organic dyes. Therefore, the development of scalable methods for highly luminescent oxide materials with fine control of size has become crucial. In this study, we suggested modified flame spray pyrolysis (FSP) as a scalable method to produce a green-light emitting phosphor-Tb-doped YO-in the nanometer size range. In our FSP method, an alkali salt (NaNO) was found to be highly effective as a size-controlling agent when it is simply mixed with other metal nitrate precursors. The FSP of the mixture solution resulted in oxide composites of YO:Tb and NaO. However, the sodium by-product was easily removed by washing with water. This salt-assisted FSP produced nano-sized and well-dispersed YO:Tb nanoparticles; their crystallinity and luminescence were higher than those of the bulk product made without the addition of the alkali salt. The nanoparticle surface was further coated with silica for biocompatibility and functionalized with amino groups for the attachment of biological molecules.
近年来，基于氧化物的纳米材料用于生物成像受到了极大关注，因为与传统有机染料相比，它们具有显著的稳定性。因此，开发可扩展的方法来制备尺寸可控的高发光氧化物材料变得至关重要。在本研究中，我们提出改进的火焰喷雾热解（FSP）作为一种可扩展的方法，以制备纳米尺寸范围内的绿色发光磷光体——掺铽氧化钇（YO:Tb）。在我们的FSP方法中，发现一种碱金属盐（NaNO）与其他金属硝酸盐前驱体简单混合时，作为尺寸控制剂非常有效。混合溶液的FSP产生了YO:Tb和NaO的氧化物复合材料。然而，通过水洗很容易去除钠副产物。这种盐辅助FSP制备出了纳米尺寸且分散良好的YO:Tb纳米颗粒；它们的结晶度和发光性能高于未添加碱金属盐制备的块状产物。纳米颗粒表面进一步用二氧化硅包覆以实现生物相容性，并用氨基官能化以连接生物分子。
