Department of Medical Science, Neuroscience and Sense Organs, Eye Clinic, University of Bari "A. Moro", Bari, Italy.
Department of Medical, Surgical, and Experimental Sciences, University of Sassari, Sassari, Italy.
Eur J Ophthalmol. 2021 May;31(3):1122-1127. doi: 10.1177/1120672120939500. Epub 2020 Jul 8.
Intravitreal corticosteroid implants based on sustained-release dexamethasone provide effective retinal delivery of drug for around 6 months for the treatment of diabetic macular edema (DME). As current recommendations on the management of patients with DME undergoing cataract surgery are limited, this article aims to highlight issues and provide guidance on the use of dexamethasone intravitreal implants (DEX-DDS) in patients with DME undergoing cataract surgery, based on the consensus findings of a panel of Italian experts.
The panel developed a survey regarding the use of DEX-DDS in patients with DME undergoing cataract surgery, following a comprehensive literature search. The results of the survey were discussed at an experts' meeting in September 2018, with a structured approach to determining consensus. The routine management of patients with DME undergoing cataract surgery was also developed for use as a basis of discussion to highlight current issues.
Eight consensus statements are presented, along with key issues that highlight controversial/outstanding issues in the use of DEX-DDS in DME patients with cataracts.
The consensus statements can help provide practical guidance for clinicians in daily practice on the rationale, patient diagnosis and selection, and optimal management of patients with DME undergoing cataract surgery.
基于持续释放地塞米松的眼内皮质类固醇植入物为治疗糖尿病性黄斑水肿（DME）提供了约 6 个月的有效视网膜药物递送。由于目前关于接受白内障手术的 DME 患者管理的建议有限，因此本文旨在基于意大利专家组的共识结果，突出问题并为接受白内障手术的 DME 患者使用地塞米松眼内植入物（DEX-DDS）提供指导。
专家组在全面文献检索后，就 DEX-DDS 在接受白内障手术的 DME 患者中的使用情况制定了一项调查。在 2018 年 9 月的专家会议上讨论了调查结果，并采用结构化方法确定了共识。还制定了接受白内障手术的 DME 患者的常规管理，用作讨论的基础，以突出当前的问题。
提出了八项共识声明，并强调了在患有白内障的 DME 患者中使用 DEX-DDS 的有争议/突出问题。
这些共识声明可以为临床医生在日常实践中提供合理的指导，包括接受白内障手术的 DME 患者的基本原理、患者诊断和选择以及最佳管理。
