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Nexilin is a New Player for Shaping T-Tubules in Cardiomyocytes.

作者信息

Wang Jinxi, Hall Duane D, Song Long-Sheng

机构信息

Division of Cardiovascular Medicine, Department of Internal Medicine, Abboud Cardiovascular Research Center (J.W., D.D.H., L.-S.S.), Carver College of Medicine, University of Iowa, Iowa City.

Fraternal Order of Eagles Diabetes Research Center (L.-S.S.), Carver College of Medicine, University of Iowa, Iowa City.

出版信息

Circ Heart Fail. 2020 Jul;13(7):e007196. doi: 10.1161/CIRCHEARTFAILURE.120.007196. Epub 2020 Jul 8.

DOI:10.1161/CIRCHEARTFAILURE.120.007196
PMID:32635767
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7375922/
Abstract
摘要

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本文引用的文献

1
Nexilin Is Necessary for Maintaining the Transverse-Axial Tubular System in Adult Cardiomyocytes.连接蛋白对于维持成年心肌细胞的横向轴向管状系统是必要的。
Circ Heart Fail. 2020 Jul;13(7):e006935. doi: 10.1161/CIRCHEARTFAILURE.120.006935. Epub 2020 Jul 8.
2
Nexilin Is a New Component of Junctional Membrane Complexes Required for Cardiac T-Tubule Formation.连接蛋白是连接复合体的一个新成分，对于心脏 T 小管的形成是必需的。
Circulation. 2019 Jul 2;140(1):55-66. doi: 10.1161/CIRCULATIONAHA.119.039751. Epub 2019 Apr 15.
3
Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca] in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity.短暂激活蛋白激酶 C 会通过改变肌动蛋白细胞骨架动力学和 T 管完整性对心肌细胞的收缩期 [Ca] 产生持久的有害影响。
J Mol Cell Cardiol. 2018 Feb;115:104-114. doi: 10.1016/j.yjmcc.2018.01.003. Epub 2018 Jan 4.
4
Calcium and Excitation-Contraction Coupling in the Heart.心脏中的钙与兴奋-收缩偶联
Circ Res. 2017 Jul 7;121(2):181-195. doi: 10.1161/CIRCRESAHA.117.310230.
5
Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo.使用CASAAV分析心肌细胞成熟，CASAAV是一种用于在体内快速剖析心肌细胞基因功能的平台。
Circ Res. 2017 Jun 9;120(12):1874-1888. doi: 10.1161/CIRCRESAHA.116.310283. Epub 2017 Mar 29.
6
Cardiac T-Tubule Microanatomy and Function.心脏横小管的微观解剖与功能
Physiol Rev. 2017 Jan;97(1):227-252. doi: 10.1152/physrev.00037.2015.
7
Microtubule-mediated defects in junctophilin-2 trafficking contribute to myocyte transverse-tubule remodeling and Ca2+ handling dysfunction in heart failure.微管介导的连接蛋白-2 转运缺陷导致心力衰竭中心肌细胞横管重构和 Ca2+处理功能障碍。
Circulation. 2014 Apr 29;129(17):1742-50. doi: 10.1161/CIRCULATIONAHA.113.008452. Epub 2014 Feb 11.
8
Ultrastructural uncoupling between T-tubules and sarcoplasmic reticulum in human heart failure.人心力衰竭时 T 管和肌浆网的超微结构解偶联。
Cardiovasc Res. 2013 May 1;98(2):269-76. doi: 10.1093/cvr/cvt030. Epub 2013 Feb 11.
9
Emerging mechanisms of T-tubule remodelling in heart failure.心力衰竭中心 T 小管重构的新兴机制。
Cardiovasc Res. 2013 May 1;98(2):204-15. doi: 10.1093/cvr/cvt020. Epub 2013 Feb 7.
10
Mutations in NEXN, a Z-disc gene, are associated with hypertrophic cardiomyopathy.NEXN 基因突变与肥厚型心肌病有关。
Am J Hum Genet. 2010 Nov 12;87(5):687-93. doi: 10.1016/j.ajhg.2010.10.002. Epub 2010 Oct 21.