Harrison G, Owens D, Holton A, Neilson D, Boot D
Department of Psychiatry, University Hospital, Nottingham.
Psychol Med. 1988 Aug;18(3):643-57. doi: 10.1017/s0033291700008321.
Several previous studies have reported increased rates of schizophrenia among Afro-Caribbean immigrants, although doubt has been cast upon the value of case-note diagnoses and retrospective case-finding. A prospective study was therefore undertaken, including all patients of Afro-Caribbean ethnic origin with a first onset psychosis presenting to the psychiatric services from a defined catchment area. Utilizing several diagnostic classifications, rates for schizophrenia were found to be substantially increased in the Afro-Caribbean community, and especially in the 'second generation' British born. Mode of onset and symptom profiles of psychoses suggest that atypical syndromes, and by implication 'misdiagnoses', do not account for reported higher rates of schizophrenic illness in these patients.
先前的几项研究报告称,非洲加勒比移民中精神分裂症的发病率有所上升,尽管有人对病例记录诊断和回顾性病例发现的价值提出了质疑。因此,开展了一项前瞻性研究,纳入了来自特定集水区、首次出现精神病症状且为非洲加勒比族裔的所有患者。采用几种诊断分类方法后发现,非洲加勒比社区中精神分裂症的发病率大幅上升,尤其是在英国出生的“第二代”人群中。精神病的发病方式和症状特征表明,非典型综合征以及由此暗示的“误诊”并不能解释这些患者中报告的精神分裂症发病率较高的情况。