Beniey Michèle, Destrempes Naomie, Coulombe Geneviève, El Khoury Mona, Nassif Edgard
Department of General Surgery, Department of Surgery, Université de Montréal, Montreal, QC, Canada.
Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Case Rep Surg. 2020 Jun 16;2020:1789185. doi: 10.1155/2020/1789185. eCollection 2020.
Merkel cell carcinoma is a rapidly progressive nonmelanoma skin cancer with a high risk of recurrence. When recurrence occurs, it is associated with poor prognosis and there is a lack of guidelines for the management of such cases. This article describes a challenging case in which the innovative use of iodine-125 radioactive seeds permitted us to precisely identify and resect two nonpalpable recurrent nodules. The safety and accuracy of the surgical procedure were compromised by the presence of scar tissue following two past resections and two courses of radiotherapy. Radioactive seed localization is a well-known procedure in breast cancer, demonstrating potential for an extended application in other cancer types and in complex clinical situations.
默克尔细胞癌是一种进展迅速的非黑色素瘤皮肤癌，复发风险高。当复发发生时，其预后较差，且缺乏针对此类病例的管理指南。本文描述了一个具有挑战性的病例，其中创新性地使用碘 - 125放射性粒子使我们能够精确识别并切除两个不可触及的复发性结节。由于过去两次切除和两个疗程的放疗后存在瘢痕组织，手术的安全性和准确性受到了影响。放射性粒子定位在乳腺癌中是一种广为人知的操作，显示出在其他癌症类型和复杂临床情况中扩展应用的潜力。
