非接触式直接选择性激光小梁成形术：光传播分析
Non-contact direct selective laser trabeculoplasty: light propagation analysis.
作者信息
Sacks Zachary S, Dobkin-Bekman Masha, Geffen Noa, Goldenfeld Mordechai, Belkin Michael
机构信息
BELKIN Laser, Ltd., 13 Gan Raveh, POB 13254, Yavne 8122214, Israel.
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
出版信息
Biomed Opt Express. 2020 May 7;11(6):2889-2904. doi: 10.1364/BOE.390849. eCollection 2020 Jun 1.
Abstract
Selective laser trabeculoplasty (SLT), used to treat glaucoma and ocular hypertension, requires the use of a gonioscope placed on the cornea to visualize and irradiate the trabecular meshwork (TM). Alternatively, non-contact direct SLT (DSLT) irradiates the TM through the overlying tissues. Here we analyze this innovative procedure using analytical modeling and Monte Carlo simulations to quantify the laser energy reaching the TM through the overlying tissues. Compared with energy launched from the laser, DSLT energy transmission to the TM is 2.8 times less than SLT, which verifies the efficacy of non-contact DSLT given the lowest reported effective SLT energies.
摘要
选择性激光小梁成形术（SLT）用于治疗青光眼和高眼压症，需要使用放置在角膜上的前房角镜来观察和照射小梁网（TM）。另外，非接触式直接SLT（DSLT）通过覆盖组织照射TM。在这里，我们使用分析模型和蒙特卡罗模拟来分析这种创新方法，以量化通过覆盖组织到达TM的激光能量。与从激光发射的能量相比，DSLT向TM的能量传输比SLT少2.8倍，鉴于报道的最低有效SLT能量，这验证了非接触式DSLT的有效性。
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