Mori Yoshimasa, Kida Yoshihisa, Matsushita Yasuhiro, Mizumatsu Shinichiro, Hatano Manabu
Radiation Oncology and Neurological Surgery, Shin-Yurigaoka General Hospital, Kawasaki, JPN.
Radiology and Radiation Oncology, Aichi Medical University, Nagakute, JPN.
Cureus. 2020 Jun 1;12(6):e8401. doi: 10.7759/cureus.8401.
The role of stereotactic radiosurgery/stereotactic radiotherapy (SRS/SRT) for malignant skull base tumors was summarized and discussed. The treatment of skull base tumors remains challenging. Their total resection is often difficult. SRS/SRT is one useful treatment option for residual or recurrent tumors after surgical resection in cases of primary skull base tumors. If skull base metastasis and skull base invasion are relatively localized, they can be candidates for SRS/SRT. Low rates of cervical lymph node involvement in early-stage (N0M0, no lymph node involvement or distant metastasis) nasal and paranasal carcinomas (NpNCa) and external auditory canal carcinomas (EACCa) have been reported in the literature. Such cases might be good candidates for SRS/SRT as the initial therapy. We previously reported the results of SRS/SRT for various malignant extra-axial skull base tumors. In addition, treatment results of early-stage head and neck carcinomas were summarized. Those of our data and those of other reported series were reviewed here to clarify the usefulness of SRS/SRT for malignant extra-axial skull base tumors.
总结并讨论了立体定向放射外科/立体定向放射治疗（SRS/SRT）在恶性颅底肿瘤中的作用。颅底肿瘤的治疗仍然具有挑战性。其全切除往往很困难。对于原发性颅底肿瘤手术切除后残留或复发的肿瘤，SRS/SRT是一种有用的治疗选择。如果颅底转移和颅底侵犯相对局限，它们可以成为SRS/SRT的候选对象。文献报道，早期（N0M0，无淋巴结受累或远处转移）鼻及鼻窦癌（NpNCa）和外耳道癌（EACCa）的颈部淋巴结受累率较低。此类病例可能是SRS/SRT作为初始治疗的良好候选对象。我们之前报道了SRS/SRT治疗各种恶性轴外颅底肿瘤的结果。此外，总结了早期头颈癌的治疗结果。在此回顾了我们的数据以及其他报道系列的数据，以阐明SRS/SRT对恶性轴外颅底肿瘤的有效性。
