Zhou He-Ye, Zong Qian-Shou, Han Ying, Chen Chuan-Feng
Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Chem Commun (Camb). 2020 Aug 27;56(69):9916-9936. doi: 10.1039/d0cc03057k.
Despite dramatic advances in the template-directed synthesis of archetypal [2]rotaxanes, higher order rotaxanes with multiple molecular components (rings or dumbbells) are relatively daunting subjects owing to their synthetic challenges. With unique interlocked architectures, higher order rotaxanes have found applications in artificial molecular machines. In this feature article, we will focus on the recent advances in higher order rotaxanes with well-defined structures. Different types of rotaxane architectures will be described, and their synthetic approaches will be highlighted. Moreover, the stimuli-responsive molecular motion with increasing complexity in these diverse architectures will also be discussed.
尽管在原型[2]轮烷的模板导向合成方面取得了巨大进展，但具有多个分子组分（环或哑铃状结构）的高阶轮烷由于其合成挑战，仍是相对艰巨的研究对象。高阶轮烷具有独特的互锁结构，已在人工分子机器中得到应用。在这篇专题文章中，我们将重点关注具有明确结构的高阶轮烷的最新进展。将描述不同类型的轮烷结构，并突出其合成方法。此外，还将讨论在这些多样结构中日益复杂的刺激响应分子运动。
