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Risk of gastric ulcer contributed by genetic polymorphisms of PSCA: A case-control study based on Chinese Han population.

作者信息

Guan Fanglin, Han Wei, Ni Tong, Zhao Longrui, Zhang Bo, Li Miao, Luo Xiaoqin, Zhang Lei, Li Xiaoming, Sun Wei, Zhang Tianxiao

机构信息

College of Medicine and Forensics, Xi'an Jiaotong University Health Science Center, Xi'an, China.

School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China.

出版信息

Gene. 2020 Oct 5;757:144941. doi: 10.1016/j.gene.2020.144941. Epub 2020 Jul 5.

DOI:10.1016/j.gene.2020.144941
PMID:32640304
Abstract
摘要

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Impact of PSCA variation on gastric ulcer susceptibility.PSCA 变异对胃溃疡易感性的影响。
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Association of PSCA rs2294008 gene variants with poor prognosis and increased susceptibility to gastric cancer and decreased risk of duodenal ulcer disease.PSCA rs2294008基因变异与胃癌预后不良、易感性增加及十二指肠溃疡疾病风险降低的关联。
Int J Cancer. 2015 Sep 15;137(6):1362-73. doi: 10.1002/ijc.29500. Epub 2015 Mar 19.
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Polymorphisms of tumor-related genes IL-10, PSCA, MTRR and NOC3L are associated with the risk of gastric cancer in the Chinese Han population.肿瘤相关基因 IL-10、PSCA、MTRR 和 NOC3L 的多态性与中国汉族人群胃癌的发病风险相关。
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Associations of genetic variants in the PSCA, MUC1 and PLCE1 genes with stomach cancer susceptibility in a Chinese population.PSCA、MUC1和PLCE1基因中的遗传变异与中国人群胃癌易感性的关联。
PLoS One. 2015 Feb 6;10(2):e0117576. doi: 10.1371/journal.pone.0117576. eCollection 2015.
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Impact of gene polymorphisms in modulating gastric cancer risk in the Chinese population.基因多态性对中国人群胃癌风险的影响。
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GWAS analysis reveals a significant contribution of PSCA to the risk of Heliobacter pylori-induced gastric atrophy.GWAS 分析显示 PSCA 对幽门螺杆菌诱导的胃萎缩风险有重要贡献。
Carcinogenesis. 2019 Jul 4;40(5):661-668. doi: 10.1093/carcin/bgz016.

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