Torrielli R, Boutin F, Rochet M, Neophytou P, Lahaye F
Département d'Anesthésie-Réanimation, maternité Pellegrin, Bordeaux.
Rev Fr Gynecol Obstet. 1988 Jul-Sep;83(7-9):509-13.
A review of 10 cases of severe obstetrical haemorrhage is presented. The etiology is not always clear. The most significant biological sign is the early, acute and marked drop of fibrinogen levels, below 1 g in 20 p. cent of the cases and 0.5 g in 50 p. cent. An early and rapid treatment is essential and based on correcting the fibrinopenia; fibrinogen, in fractioned form, at a mean dose of 3 g, reduces the duration of the syndrome and minimize the risks of complications. In the acute phase, heparin therapy must be avoided because it might aggravate the haemorrhage.
本文报告了10例严重产科出血病例。病因并不总是明确的。最显著的生物学标志是纤维蛋白原水平早期、急性且显著下降，20%的病例低于1g，50%的病例低于0.5g。早期快速治疗至关重要，且基于纠正纤维蛋白原减少；分馏形式的纤维蛋白原，平均剂量为3g，可缩短综合征持续时间并将并发症风险降至最低。在急性期，必须避免肝素治疗，因为它可能会加重出血。
