Emeritus Professor of Cardiology, School of Medicine, Salvador University, President, Academia, Nacional de Medicina de Buenos Aires, Buenos Aires, Argentina.
Curr Cardiol Rev. 2021;17(1):31-40. doi: 10.2174/1573403X16666200708111928.
Many advances in the knowledge of medical science are due to the observation of an unknown phenomenon that remains an open question. A plausible hypothesis must be demonstrated and proved through a scientific method in order to be accepted by the scientific community and the same results must be reached by following either the same or different techniques. The original case described by Rosenbaum MB et al., in this review triggered a series of anatomic and physiologic investigations with clinical and experimental observations that supported the trifascicular nature of the intraventricular conduction system of the heart and the concept of hemiblocks. The recognition and description of the left fascicular blocks made by the Argentinian School of Electrocardiology bridged an important gap in electrocardiography and many electrocardiograms that could not be explained until that moment could finally be understood. This review intends to redefine reliable criteria for the electrocardiographic and vectorcardiographic diagnosis of left fascicular blocks [hemiblocks]. The anatomy of the left bundle branch is also discussed to better understand the incidence, prevalence, clinical significance and main causes of left anterior and left posterior hemiblock either isolated or associated with right bundle branch block. This review offers the reader a reappraisal of the trifascicular nature of the intraventricular conduction system regarding the anatomy of the left bundle branch system and its pathophysiological and clinical significance.
许多医学科学知识的进步都归因于对一个未知现象的观察,而这个现象仍然是一个悬而未决的问题。一个合理的假设必须通过科学方法来证明和验证,才能被科学界所接受,并且必须采用相同或不同的技术才能得出相同的结果。罗森鲍姆等人在这篇综述中描述的原始病例引发了一系列解剖和生理研究,以及临床和实验观察,这些观察结果支持了心脏室内传导系统的三分支性质和半分支概念。阿根廷电生理学会对左束支阻滞的识别和描述填补了心电图学的一个重要空白,许多在此之前无法解释的心电图现在终于可以得到理解。本篇综述旨在重新定义心电图和向量心电图诊断左束支阻滞(半分支阻滞)的可靠标准。还讨论了左束支的解剖结构,以便更好地理解孤立或与右束支阻滞相关的左前和左后半分支阻滞的发生率、患病率、临床意义和主要原因。本篇综述为读者提供了对室内传导系统三分支性质的重新评估,涉及左束支系统的解剖结构及其病理生理和临床意义。