Elizari Marcelo V, Acunzo Rafael S, Ferreiro Marcela
Division of Cardiology, Ramos Mejía Hospital, Urquiza 609, Buenos Aires C1221ADC, Argentina.
Circulation. 2007 Mar 6;115(9):1154-63. doi: 10.1161/CIRCULATIONAHA.106.637389.
The trifascicular nature of the intraventricular conduction system and the concept of trifascicular block and hemiblock were described by Rosenbaum and his coworkers in 1968. Since then, anatomic, pathological, electrophysiological, and clinical studies have confirmed the original description and scarce advances have been developed on the subject. In the present study, we attempt to review and redefine reliable criteria for the electrocardiographic and vectorcardiographic diagnosis of left anterior and posterior hemiblock. One of the most important problems related to hemiblocks is that they may simulate or conceal the electrocardiographic signs of myocardial infarction or myocardial ischemia and may mask or simulate ventricular hypertrophy. Illustrative examples of these associations are shown to help the interpretation of electrocardiograms. The incidence and prevalence of the hemiblocks is presented based on studies performed in hospital patients and general populations. One of the most common causes of hemiblocks is coronary artery disease, and there is a particularly frequent association between anteroseptal myocardial infarction and left anterior hemiblock. The second most important cause is arterial hypertension, followed by cardiomyopathies and Lev and Lenègre diseases. The hemiblocks may also occur in aortic heart disease and congenital cardiopathies. Left anterior hemiblock is more common in men and increases in frequency with advancing age. Evidence is presented regarding the relationship of spontaneous closure of ventricular septal defects, which may explain the finding of this and other conduction defects in young populations. Isolated left anterior hemiblock is a relatively frequent finding in subjects devoid of evidence of structural heart disease. Conversely, isolated left posterior hemiblock is a very rare finding; its prognostic significance is unknown and is commonly associated with right bundle-branch block. The most remarkable feature of this association is that the prognosis is much more serious with a great propensity to develop complete atrioventricular block and Adams-Stoke seizures.
1968年,罗森鲍姆及其同事描述了心室内传导系统的三分支性质以及三分支阻滞和半阻滞的概念。从那时起,解剖学、病理学、电生理学和临床研究证实了最初的描述,并且在该主题上几乎没有取得进展。在本研究中,我们试图回顾并重新定义左前半阻滞和左后半阻滞心电图及向量心电图诊断的可靠标准。与半阻滞相关的最重要问题之一是它们可能模拟或掩盖心肌梗死或心肌缺血的心电图征象,并且可能掩盖或模拟心室肥大。文中展示了这些关联的示例以帮助解读心电图。基于对住院患者和普通人群的研究,呈现了半阻滞的发病率和患病率。半阻滞最常见的原因之一是冠状动脉疾病,并且前间隔心肌梗死与左前半阻滞之间存在特别频繁的关联。第二重要的原因是动脉高血压,其次是心肌病以及Lev病和Lenègre病。半阻滞也可能发生在主动脉性心脏病和先天性心脏病中。左前半阻滞在男性中更常见,并且频率随年龄增长而增加。文中提供了关于室间隔缺损自然闭合关系的证据,这可能解释了年轻人群中这种及其他传导缺陷的发现。孤立性左前半阻滞在无结构性心脏病证据的受试者中是相对常见的发现。相反,孤立性左后半阻滞是非常罕见的发现;其预后意义尚不清楚,并且通常与右束支阻滞相关。这种关联最显著的特征是预后严重得多,极有可能发展为完全性房室阻滞和阿-斯发作。