Department of Pathology, University of Michigan, Ann Arbor, Michigan.
Department of Pathology and Laboratory Medicine, Weill Cornell College of Medicine, New York, New York.
J Am Soc Cytopathol. 2020 Sep-Oct;9(5):405-421. doi: 10.1016/j.jasc.2020.05.014. Epub 2020 Jun 10.
Both fine-needle aspiration (FNA) and core needle biopsy (CNB) are widely used to obtain liver biopsy specimens, particularly from mass lesions. However, the advantages and disadvantages of FNA versus CNB in terms of appropriate use, diagnostic yield, complications, and whether or not specimens should be handled by cytopathologists, surgical pathologists, or both remain subjects of controversy. This review addresses the issues of sample adequacy, appropriate use of each technique and complications, and challenges regarding the diagnosis of both hepatic tumors and non-neoplastic liver disease.
细针抽吸（FNA）和核心针活检（CNB）均广泛用于获取肝活检标本，尤其是来源于肿块病变的标本。然而，在适当的应用、诊断率、并发症以及标本应由细胞病理学家、外科病理学家还是两者共同处理等方面，FNA 与 CNB 的优缺点仍然存在争议。这篇综述探讨了样本充足性、每种技术的适当应用和并发症，以及诊断肝肿瘤和非肿瘤性肝病的挑战等问题。
