Mbuagbaw Lawrence, Tharao Wangari, Husbands Winston, Nelson Laron E, Aden Muna, Arnold Keresa, Baidoobonso Shamara, Dabone Charles, Dryden OmiSoore, Etowa Egbe, Hamid Jemila, Jackson-Best Fatimah, Kohoun Bagnini, Lawson Daeria O, Lofters Aisha K, Luyombya Henry, Mbulaheni Tola, Mkandawire Paul, Ndungu Mary, Nyambi Agatha, Obiorah Suzanne, Ongoiba Fanta, Ongolo-Zogo Clémence, Oraka Chinedu, Shahin Rita, Yaya Sanni, Hendricks Andrew, Gebremeskel Aster, Inoua Haoua, Etowa Josephine
Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada
Women's Health in Women's Hands Community Health Centre, Toronto, Ontario, Canada.
BMJ Open. 2020 Jul 8;10(7):e036259. doi: 10.1136/bmjopen-2019-036259.
African, Caribbean and Black (ACB) communities are disproportionately infected by HIV in Ontario, Canada. They constitute only 5% of the population of Ontario yet account for 25% of new diagnoses of HIV. The aim of this study is to understand underlying factors that augment the HIV risk in ACB communities and to inform policy and practice in Ontario.
We will conduct a cross-sectional study of first-generation and second-generation ACB adults aged 15-64 in Toronto (n=1000) and Ottawa (n=500) and collect data on sociodemographic information, sexual behaviours, substance use, blood donation, access and use of health services and HIV-related care. We will use dried blood spot testing to determine the incidence and prevalence of HIV infection among ACB people, and link participant data to administrative databases to investigate health service access and use. Factors associated with key outcomes (HIV infection, testing behaviours, knowledge about HIV transmission and acquisition, HIV vulnerability, access and use of health services) will be evaluated using generalised linear mixed models, adjusted for relevant covariates.
This study has been reviewed and approved by the following Research Ethics Boards: Toronto Public Health, Ottawa Public Health, Laurentian University; the University of Ottawa and the University of Toronto. Our findings will be disseminated as community reports, fact sheets, digital stories, oral and poster presentations, peer-reviewed manuscripts and social media.
在加拿大安大略省，非洲、加勒比和黑人（ACB）社区感染艾滋病毒的比例过高。他们仅占安大略省人口的5%，却占新诊断艾滋病毒病例的25%。本研究的目的是了解增加ACB社区艾滋病毒风险的潜在因素，并为安大略省的政策和实践提供信息。
我们将对多伦多（n = 1000）和渥太华（n = 500）年龄在15 - 64岁的第一代和第二代ACB成年人进行横断面研究，收集社会人口学信息、性行为、物质使用、献血、医疗服务的可及性和使用情况以及与艾滋病毒相关护理的数据。我们将使用干血斑检测来确定ACB人群中艾滋病毒感染的发病率和患病率，并将参与者数据与行政数据库相链接以调查医疗服务的可及性和使用情况。将使用广义线性混合模型评估与关键结果（艾滋病毒感染、检测行为、艾滋病毒传播和感染知识、艾滋病毒易感性、医疗服务的可及性和使用情况）相关的因素，并对相关协变量进行调整。
本研究已获得以下研究伦理委员会的审查和批准：多伦多公共卫生部门、渥太华公共卫生部门、劳伦森大学、渥太华大学和多伦多大学。我们的研究结果将以社区报告、情况说明书、数字故事、口头和海报展示、同行评审手稿以及社交媒体等形式进行传播。
