Division of Gastroenterology, Faculty of Medicine, University of Tsukuba, Japan.
Department of Pathology, University of Tsukuba Hospital, Japan.
Intern Med. 2020 Oct 15;59(20):2505-2509. doi: 10.2169/internalmedicine.4584-20. Epub 2020 Jul 7.
A 70-year-old woman was referred to our department due to a solitary mediastinal tumor which gradually grew near the site of anastomosis for 8 years after radical surgery of esophageal squamous cell carcinoma. It was difficult to distinguish the lymph node recurrence of esophageal cancer from another tumor of unknown primary origin. Endoscopic ultrasound-guided fine-needle aspiration was performed, and the tumor was diagnosed to be neuroendocrine carcinoma. She received concurrent chemoradiotherapy with etoposide plus cisplatin. After the completion of chemoradiotherapy, the tumor disappeared. A solitary growing tumor which develops after radical resection of cancer would be better to be examined histologically in order to make an accurate diagnosis and select the most appropriate treatment.
一位 70 岁女性因孤立性纵隔肿瘤就诊，该肿瘤位于 8 年前行食管鳞癌根治术后吻合口附近，逐渐增大。难以将食管癌的淋巴结复发与不明原发灶的另一肿瘤区分开。行超声内镜引导下细针抽吸活检，诊断为神经内分泌癌。她接受依托泊苷联合顺铂同步放化疗。放化疗完成后，肿瘤消失。癌症根治性切除术后出现的孤立性生长肿瘤，最好进行组织学检查，以明确诊断并选择最合适的治疗方法。
