Bratina Petra, Kersnik Levart Tanja
Tanja Kersnik Levart, Department of Nephrology, Division of Pediatrics, University Medical Centre, Bohoričeva 20, 1000 Ljubljana, Slovenia,
Croat Med J. 2020 Jul 5;61(3):246-251. doi: 10.3325/cmj.2020.61.246.
To assess the association between the Urinary Tract Dilatation (UTD) Antenatal (A) and Postnatal (P) Classification System grade and the outcome in term newborns.
This retrospective study enrolled 166 term newborns (71% boys, 206 ureterorenal units) evaluated for unilateral or bilateral UTD in the Neonatology Department of Ljubljana University Medical Center from 2012 to 2018. Data on family history, sex, gestational age, birth weight, head circumference, Apgar score, possible oligohydramnios, indication for and age at first postnatal ultrasound, time of follow-up, and clinical outcome were collected. Radiology records were reviewed to grade UTD according to the Multidisciplinary Consensus on the Classification of Prenatal and Postnatal UTD.
The majority of ureterorenal units with UTD A 2-3 had UTD P 2 or 3. Spontaneous resolution, specific uropathy, the need for surgery, and the risk of urinary tract infection were all significantly associated with the UTD P grade. No patient experienced renal dysfunction at the end of follow-up (12-48 months, median 24 months), and therefore this parameter was not associated with the UTD P grade.
The UTD grade was associated with the probability of spontaneous resolution, time to its occurrence, specific uropathies urinary tract infection, and risk for surgery. However, no association with renal dysfunction was established.
评估产前（A）和产后（P）泌尿系统扩张（UTD）分类系统分级与足月儿结局之间的关联。
这项回顾性研究纳入了2012年至2018年在卢布尔雅那大学医学中心新生儿科接受单侧或双侧UTD评估的166例足月儿（71%为男孩，206个输尿管肾单位）。收集了家族史、性别、胎龄、出生体重、头围、阿氏评分、可能的羊水过少情况、产后首次超声检查的指征和年龄、随访时间以及临床结局等数据。根据产前和产后UTD分类的多学科共识，对放射学记录进行审查以对UTD进行分级。
大多数产前UTD A 2 - 3级的输尿管肾单位产后UTD为P 2或3级。自然缓解、特定泌尿系统疾病、手术需求以及尿路感染风险均与产后UTD分级显著相关。在随访结束时（12 - 48个月，中位时间24个月），没有患者出现肾功能障碍，因此该参数与产后UTD分级无关。
UTD分级与自然缓解的概率、自然缓解发生的时间、特定泌尿系统疾病、尿路感染以及手术风险相关。然而，未发现与肾功能障碍有关联。
