Maramattom Boby Varkey
Department of Neurology, Aster Medcity, Kochi, Kerala, India.
Neurol India. 2020 May-Jun;68(3):660-664. doi: 10.4103/0028-3886.288983.
There could be an association between cryptococcal meningitis and the later development of moyamoya syndrome. We performed serial clinical and radiological assessments in an immunosuppressed post-renal transplant patient who had previously suffered from cryptococcal meningitis and then went on to develop a moyamoya syndrome (MMS). We also performed a literature search and review of post-infectious MMS cases from 1976 to 2019. The clinical course and radiological findings were consistent with a diagnosis of MMS. After exclusion of other causes, accelerated MMS secondary to cryptococcal meningitis, developing over 1-2 months, was considered. Our observation adds further evidence to the concept of a post-infectious MMS. This report is the first to add fungal meningitis to the etiology of an MMS.
隐球菌性脑膜炎与烟雾病综合征的后期发展之间可能存在关联。我们对一名免疫抑制的肾移植术后患者进行了系列临床和影像学评估,该患者曾患隐球菌性脑膜炎,随后发展为烟雾病综合征(MMS)。我们还对1976年至2019年感染后MMS病例进行了文献检索和综述。临床病程和影像学表现符合MMS的诊断。在排除其他病因后,考虑为继发于隐球菌性脑膜炎的快速进展型MMS,病程在1 - 2个月内。我们的观察为感染后MMS的概念提供了进一步证据。本报告首次将真菌性脑膜炎纳入MMS的病因。