From the Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, New York.
A A Pract. 2020 Jun;14(8):e01248. doi: 10.1213/XAA.0000000000001248.
Midazolam is commonly used for sedation during procedures because of its relative safety and predictability. Still, some rare undesirable medication reactions have been described. We report a case in which midazolam given before a peripheral nerve block caused acute onset dyskinetic extrapyramidal symptoms. These symptoms ultimately resolved following reversal of the midazolam with flumazenil. Given the widespread and multidisciplinary use of midazolam, practitioners should be aware of the potential for rare adverse reactions and be prepared to manage these scenarios.
咪达唑仑由于其相对安全性和可预测性，常用于手术镇静。然而，仍有一些罕见的不良药物反应被描述。我们报告了一例在周围神经阻滞前给予咪达唑仑引起急性发作的不自主锥体外系症状的病例。这些症状最终在使用氟马西尼逆转咪达唑仑后得到缓解。鉴于咪达唑仑的广泛和多学科应用，从业者应意识到罕见不良反应的可能性，并准备好管理这些情况。
