Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao yang Hospital, Capital Medical University, Beijing, China.
J Int Med Res. 2020 Jul;48(7):300060520926010. doi: 10.1177/0300060520926010.
This study aimed to evaluate the relationship between obstructive sleep apnea (OSA) and the fraction of exhaled nitric oxide (F), and to assess the effect of risk factors of airway inflammation on OSA.
Medical records of patients in the Respiratory Sleep Center at Chao-Yang Hospital in Beijing between January 2015 and June 2017 were analyzed. All patients were diagnosed with OSA. Data of the medical history, clinical examinations, F, and upper airway computed tomographic findings were collected. Logistic regression was used to evaluate risk factors of OSA.
A total of 181 patients were admitted to the Respiratory Sleep Center during the study and 170 had a diagnosis of OSA and were included in the study. Single factor analysis showed that male sex, age, body mass index, smoking index, alcohol consumption, F, soft palate thickness, soft palate length, the narrowest transverse diameter of the upper airway, tonsil size, and nasal sinusitis were risk factors for sleep-disordered breathing and disease severity.
Male sex, age, body mass index, F, the narrowest transverse diameter of the upper airway, and normal tonsil size are associated with OSA and disease severity. The severity of OSA is associated with F levels.
本研究旨在评估阻塞性睡眠呼吸暂停（OSA）与呼出气一氧化氮分数（F）之间的关系，并评估气道炎症危险因素对 OSA 的影响。
分析了 2015 年 1 月至 2017 年 6 月在北京朝阳医院呼吸睡眠中心就诊的患者的病历。所有患者均被诊断为 OSA。收集了病史、临床检查、F 和上气道计算机断层扫描的结果。采用 logistic 回归评估 OSA 的危险因素。
研究期间，共有 181 名患者入住呼吸睡眠中心，其中 170 名被诊断为 OSA 并纳入研究。单因素分析表明，男性、年龄、体重指数、吸烟指数、饮酒、F、软腭厚度、软腭长度、上气道最小横径、扁桃体大小和鼻鼻窦炎是睡眠呼吸障碍和疾病严重程度的危险因素。
男性、年龄、体重指数、F、上气道最小横径和正常扁桃体大小与 OSA 和疾病严重程度相关。OSA 的严重程度与 F 水平相关。
