Wen Daizong, Yu Jinjin, Zeng Zhenhai, McAlinden Colm, Hu Liang, Feng Ke, Wang Yiran, Song Benhao, Chen Sisi, Ning Rui, Jin Yili, Wang Qinmei, Yu A-Yong, Huang Jinhai
J Refract Surg. 2020 Jul 1;36(7):481-490. doi: 10.3928/1081597X-20200519-04.
To systematically compare and rank the predictability of no-history intraocular lens (IOL) power calculation methods after myopic laser refractive surgery.
PubMed, Embase, the Cochrane Library, and the U.S. trial registry (www.ClinicalTrial.gov) were used to systematically search trials published up to August 2019. Included were case series studies reporting the following outcomes in patients with cataract undergoing phacoemulsification after laser refractive surgery: percentage of eyes with a refractive prediction error (PE) within ±0.50 and ±1.00 diopters (D), mean absolute error (MAE), and median absolute error (MedAE). A network meta-analysis was conducted using the STATA software version 13.1 (STATACorp LLC).
Nineteen studies involving 1,098 eyes and 19 formulas were identified. A network meta-analysis for the percentage of eyes with a PE within ±0.50 D found that ray-tracing (Okulix), intraoperative aberrometry (Optiwave Refractive Analysis [ORA]), BESSt, and Seitz/Speicher/Savini (Triple-S) (D-K SRK/T), and Fourier-Domain OCT-Based formulas were more predictive than the Wang/Koch/Maloney, Shammas-PL, modified Rosa, Ferrara, and Equivalent K reading at 4.5 mm using the Double-K Holladay 1 formulas. With regard to ranking, the top four formulas as per the surface under the cumulative ranking curve (SUCRA) values for the percentage of eyes with a PE within ±0.50 D were the Okulix, ORA, BESSt, and Triple-S (D-K SRK/T). With regard to MAE, the ORA showed lower errors when compared to the Shammas-PL formula. In this regard, the top four formulas based on the SUCRA values were the Triple-S, BESSt, ORA, and Fourier-Domain OCT-Based formulas. The SToP (SRK/T), ORA, Fourier-Domain OCT-Based, and BESSt formulas had the lowest MedAE.
Considering all three outcome measures of highest percentages of eyes with a PE within ±0.50 and ±1.00 D, lowest MAE, and lowest MedAE, the top three no-history formulas for IOL power calculation in eyes with previous myopic corneal laser refractive surgery were: ORA, BESSt, and Triple-S (D-K SRK/T). [J Refract Surg. 2020;36(7):481-490.].
系统比较并排序近视激光屈光手术后无手术史人工晶状体（IOL）屈光力计算方法的可预测性。
使用PubMed、Embase、Cochrane图书馆和美国试验注册库（www.ClinicalTrial.gov）系统检索截至2019年8月发表的试验。纳入的病例系列研究报告了接受激光屈光手术后行白内障超声乳化术患者的以下结果：屈光预测误差（PE）在±0.50和±1.00屈光度（D）以内的眼的百分比、平均绝对误差（MAE）和中位数绝对误差（MedAE）。使用STATA软件版本13.1（STATACorp LLC）进行网状Meta分析。
确定了19项涉及1098只眼和19种公式的研究。对PE在±0.50 D以内的眼的百分比进行网状Meta分析发现，光线追踪法（Okulix）、术中像差仪法（Optiwave屈光分析[ORA]）、BESSt法和Seitz/Speicher/Savini法（Triple-S）（D-K SRK/T）以及基于傅里叶域光学相干断层扫描的公式比Wang/Koch/Maloney法、Shammas-PL法、改良Rosa法、Ferrara法以及使用Double-K Holladay 1公式在4.5 mm处的等效K读数法更具预测性。在排序方面，根据PE在±0.50 D以内的眼的百分比的累积排序曲线下面积（SUCRA）值，排名前四位的公式是Okulix、ORA、BESSt和Triple-S（D-K SRK/T）。关于MAE，与Shammas-PL公式相比，ORA显示出更低的误差。在这方面，基于SUCRA值排名前四位的公式是Triple-S、BESSt、ORA和基于傅里叶域光学相干断层扫描的公式。SToP（SRK/T）、ORA、基于傅里叶域光学相干断层扫描的公式和BESSt公式的MedAE最低。
考虑到PE在±0.50和±1.00 D以内的眼的百分比最高、MAE最低和MedAE最低这三个结果指标，对于既往有近视角膜激光屈光手术史的眼，IOL屈光力计算的前三种无手术史公式为：ORA、BESSt和Triple-S（D-K SRK/T）。[《屈光手术杂志》。2020；36（7）：481-490。]
