Hand Research Laboratory, Department of Biomedical Engineering, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopedic Surgery, Cleveland Clinic, Cleveland, Ohio, USA.
Muscle Nerve. 2020 Oct;62(4):522-527. doi: 10.1002/mus.27017. Epub 2020 Aug 5.
The purpose of this study was to investigate in vivo median nerve longitudinal mobility in different segments of the carpal tunnel associated with active finger motion in carpal tunnel syndrome (CTS) patients in a comparison with healthy controls.
Eleven healthy volunteers and 11 CTS patients participated in this study. Dynamic ultrasound images captured location-dependent longitudinal median nerve mobility within the carpal tunnel during finger flexion at the metacarpophalangeal joints using a speckle cross-correlation algorithm.
Median nerve longitudinal mobility in the carpal tunnel was significantly smaller in CTS patients (0.0037 ± 0.0011 mm/degree) compared with controls (0.0082 ± 0.0026 mm/degree) (P < .05), especially in the proximal (0.0064 vs 0.0132 mm/degree on average) and middle (0.0033 vs 0.0074 mm/degree on average) carpal tunnel sections.
Median nerve mobility can potentially serve as a biomechanical marker when diagnosing CTS, or when assessing the effectiveness of surgical and conservative treatments.
本研究旨在探讨腕管综合征（CTS）患者与健康对照组相比，在主动手指运动时腕管内正中神经各节段的纵向活动性。
11 名健康志愿者和 11 名 CTS 患者参与了这项研究。在掌指关节处进行手指弯曲运动时，使用散斑互相关算法捕获动态超声图像，以获取腕管内正中神经在依赖位置的纵向活动性。
与对照组（0.0082±0.0026mm/度）相比，CTS 患者的腕管内正中神经纵向活动性明显较小（0.0037±0.0011mm/度）（P<.05），尤其是在近侧（平均 0.0064 与 0.0132mm/度）和中间（平均 0.0033 与 0.0074mm/度）腕管段。
正中神经的活动性可能可作为诊断 CTS 的生物力学标志物，或用于评估手术和保守治疗的效果。
