Central Centrifugal Cicatricial Alopecia

Central centrifugal cicatricial alopecia (CCCA) is a unique form of scarring alopecia that clinically presents as patches of permanent hair loss on the vertex or crown of the scalp and spreads centrifugally. (See  Central Centrifugal Cicatricial Alopecia.) This type of hair loss is associated with signs and symptoms of inflammation. CCCA is a common condition that usually affects women of African descent, and it runs in families. Limited data is available regarding the treatment of CCCA. The treatment modalities include topical and systemic corticosteroids and oral tetracyclines with limited response. The prognosis varies, and it widely depends upon the duration and nature of the disease.