Zhang Jun, Zhang Weidong, Min Meilin, Pan Yunbo
Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine, Wuxi, China.
Wuxi Higher Health Vocational Technology School, Wuxi, China.
Int J Surg Case Rep. 2020;73:71-74. doi: 10.1016/j.ijscr.2020.05.038. Epub 2020 Jun 20.
Axillary accessory breast cancer and persistent left superior vena cava (PLSVC) are rare clinically. Many controversial treatments for accessory breast cancer are worth discussing and learning.
A 48-year-old woman presented with biopsy histopathology confirmed. Right axillary mass biopsy pathology showed mucinous adenocarcinoma of accessory breast. She concerned that the axillary accessory breast cancer was more likely to metastasize and unsure about whether to remove the breast. She accepted extended right axillary accessory breast resection plus ipsilateral axillary lymph node dissection (ALND) and received chemotherapy. She was found to have a PLSVC before chemotherapy.
Is there a need to remove the breast and perform ALND during axillary accessory breast cancer surgery? Is sentinel lymph node biopsy (SLNB) appropriate for axillary accessory breast cancer surgery? Can negative SLNB for axillary accessory breast cancer avoid ALND? Does accessory breast cancer without axillary lymph node metastasis require local radiotherapy? Does PLSVC impact the use of peripherally inserted central catheters (PICC) tubes during chemotherapy? Patients with accessory breast cancer without breast invasion should undergo local extended resection and ALND. SLNB for accessory breast cancer cannot instead of ALND. We recommend routine axillary radiotherapy after accessory breast cancer surgery. If it is determined that the tip of PICC is not in the coronary sinus of PLSVC, PLSVC does not affect chemotherapy.
Many treatment strategies for accessory breast cancer require more evidence from evidence-based medicine. It is imperative to conduct multi-center accessory breast cancer research.
腋窝副乳腺癌和永存左上腔静脉(PLSVC)在临床上较为罕见。许多关于副乳腺癌的有争议的治疗方法值得探讨和学习。
一名48岁女性,活检组织病理学确诊。右腋窝肿块活检病理显示为副乳腺黏液腺癌。她担心腋窝副乳腺癌更容易转移,不确定是否要切除乳房。她接受了右腋窝扩大副乳腺切除术加同侧腋窝淋巴结清扫术(ALND)并接受了化疗。化疗前发现她有PLSVC。
腋窝副乳腺癌手术时是否需要切除乳房并进行ALND?前哨淋巴结活检(SLNB)是否适用于腋窝副乳腺癌手术?腋窝副乳腺癌SLNB阴性能否避免ALND?无腋窝淋巴结转移的副乳腺癌是否需要局部放疗?PLSVC是否会影响化疗期间外周静脉穿刺中心静脉导管(PICC)的使用?无乳腺侵犯的副乳腺癌患者应进行局部扩大切除和ALND。副乳腺癌的SLNB不能替代ALND。我们建议副乳腺癌手术后常规进行腋窝放疗。如果确定PICC尖端不在PLSVC的冠状窦内,PLSVC不影响化疗。
许多副乳腺癌的治疗策略需要更多循证医学证据。开展多中心副乳腺癌研究势在必行。