Koizumi J, Ofuku K, Sakuma K, Shiraishi H, Iio M, Nawano S
Department of Psychiatry, University of Tsukuba, Japan.
J Neurol Neurosurg Psychiatry. 1988 Jul;51(7):987-90. doi: 10.1136/jnnp.51.7.987.
CNS changes in a case of Usher's syndrome associated with schizophrenia-like mental disorder were observed by CT, MRI and PET. The neuro-radiological findings of the case demonstrate the degenerative and metabolic alterations in various regions of cortex, white matter and subcortical areas in the brain. Mental disorder of the case is almost indistinguishable from that of schizophrenia, but the psychotic feature is regarded as an atypical or mixed organic brain syndrome according to the classification in the third edition of the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM-III).
通过CT、MRI和PET观察了一例与精神分裂症样精神障碍相关的Usher综合征患者的中枢神经系统变化。该病例的神经放射学检查结果显示了大脑皮质、白质和皮质下区域不同部位的退行性和代谢改变。该病例的精神障碍与精神分裂症几乎难以区分，但根据美国精神病学协会《精神障碍诊断与统计手册》第三版（DSM-III）中的分类，其精神病性特征被视为一种非典型或混合性器质性脑综合征。
