Balkarov I M, Maksimov N M, Aleksandrovskaia T N, Poliantseva L R
Ter Arkh. 1988;60(6):37-9.
Of 3200 patients admitted to the nephrology department within several years, hyperuricemia was detected in 696. Excluding from this number persons with signs of chronic renal insufficiency (146 persons) and patients who were treated by diuretics (89), the frequency of hyperuricemia was 16.2% which exceeded almost 2-fold (9.2%) the value determined during the examination of 594 healthy persons. The authors discussed a possibility of early development of renal pathology in purine metabolic derangement with hyperuricosuric and hyperuricemic stages characterized by certain clinical peculiarities, including a possibility of development of immune complex nephritis.
在几年内收治于肾病科的3200例患者中，检测到696例高尿酸血症。排除有慢性肾功能不全体征的患者（146例）和使用利尿剂治疗的患者（89例）后，高尿酸血症的发生率为16.2%，几乎超过了在594例健康人检查中所确定值（9.2%）的2倍。作者讨论了嘌呤代谢紊乱伴高尿酸尿症和高尿酸血症阶段早期发生肾脏病理改变的可能性，这些阶段具有某些临床特点，包括发生免疫复合物肾炎的可能性。
