Guangdong Mental Health Center, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Science, Guangzhou, China.
School of Computer Science, South China Normal University, Guangzhou, China.
BMC Med Inform Decis Mak. 2020 Jul 9;20(Suppl 3):132. doi: 10.1186/s12911-020-1125-0.
With China experiencing unprecedented economic development and social change over the past three decades, Chinese policy makers and health care professionals have come to view mental health as an important outcome to monitor. Our study conducted an epidemiological study of psychosis in Guangdong province, with 20 million real-world follow-up records in the last decade.
Data was collected from Guangdong mental health information platform from 2010 to 2019, which had standardized disease registration and follow-up management for nearly 600,000 patients with six categories of mental diseases and 400,000 patients with schizophrenia. We conducted clinical staging for the disease course of the patients and divided the data with various factors into different stages of disease. Quantitative analysis was utilized to investigate the high relevant indicators to the disease. The results were projected on geography map for regional distribution analysis.
The majority cases of mental disease incidence were between the age of 15 and 29, while the peak age for both male and female was between 20 to 24 years old. The disease course with the largest number of patients' cases was between 5 to 10 years. The therapeutic effect of patients gradually decreased with the development of disease course, while the risk increased with the disease course. The analysis of influencing factors showed that poor economic conditions incurred higher risk scores, and good medication adherence was effective in improving treatment outcomes. In addition, receiving good education contributed to the reduction of the risk of schizophrenia and the improvement of the efficiency of early treatment. Through the analysis of regional distribution of schizophrenia disease, developed economic conditions and favorable resource conditions could promote the reduction of disease risk, while in economically backward regions, it often accompanied with lower therapeutic effect and higher disease risk.
Certain demographic factors had a relatively prominent impact on the therapeutic effect and risk of schizophrenia, such as high-quality medication adherence. Therapeutic effect and risk were highly correlated. Backward economic conditions often associated with poor efficacy and higher risk assessment, and the developed economy and better medical resource are beneficial for the treatment of psychotic.
过去三十年来，中国经历了前所未有的经济发展和社会变革，政策制定者和卫生保健专业人员开始将精神健康视为需要监测的重要结果。我们的研究对广东省的精神病进行了流行病学研究，利用过去十年的 2000 万例真实世界随访记录。
数据来自 2010 年至 2019 年的广东省心理健康信息平台，该平台对六类精神疾病的近 60 万名患者和 40 万名精神分裂症患者进行了标准化疾病登记和随访管理。我们对患者的疾病病程进行了临床分期，并根据各种因素将数据分为不同的疾病阶段。采用定量分析方法调查与疾病高度相关的指标，将结果投射到地理地图上进行区域分布分析。
精神疾病发病的大多数病例发生在 15 至 29 岁之间，而男性和女性的发病高峰年龄均在 20 至 24 岁之间。患者病例数量最多的疾病病程在 5 至 10 年之间。随着疾病病程的发展，患者的治疗效果逐渐下降，而风险则随着疾病病程的发展而增加。影响因素分析表明，经济条件差的患者风险评分较高，良好的药物依从性可有效改善治疗效果。此外，接受良好的教育有助于降低精神分裂症的发病风险，提高早期治疗的效果。通过对精神分裂症疾病的区域分布分析发现，经济发达条件和有利的资源条件可以降低疾病风险，而在经济落后地区，往往伴随着较低的治疗效果和较高的疾病风险。
某些人口统计学因素对精神分裂症的治疗效果和风险有相对突出的影响，如高质量的药物依从性。治疗效果和风险高度相关。经济落后条件往往与疗效不佳和风险评估较高相关，发达的经济和更好的医疗资源有利于精神疾病的治疗。
