Department of Family and Community Medicine, Baycrest, Toronto, Ontario, Canada; Division of Palliative Care, Department of Family and Community Medicine, Faculty of Medicine, Toronto, Ontario, Canada; Department of Human Biology, University of Toronto, Toronto, Ontario, Canada.
Department of Human Biology, University of Toronto, Toronto, Ontario, Canada; Department of Human Biology, Toronto, Ontario, Canada.
J Am Med Dir Assoc. 2020 Sep;21(9):1197-1206.e2. doi: 10.1016/j.jamda.2020.05.010. Epub 2020 Jul 6.
To determine whether single interventions (SI), multifactorial interventions (MI), or multiple component interventions (MCI) including vitamin D supplementation prevent the incidence of falls and fall risk factors among older adults who are community-dwelling or living in long-term care facilities.
Systematic review.
PubMed, Scopus, MEDLINE, and Cochrane were searched with restrictions applied to publication year (2015‒2019) and language (limited to studies published in English). After duplicate removal and title and abstract screening, 2 authors independently identified eligible studies on the basis of inclusion criteria. Risk of bias and quality of evidence were assessed.
Thirty-four studies were included after screening titles and abstracts from 855 citations and 129 full-text articles. Thirteen randomized-controlled trials and clinical trials (5 on MI, 1 on MCI, and 7 on SI) including 2232 participants and 21 systematic reviews (assessing SI, MI, MCI, or all) were extracted for qualitative synthesis. Fifteen out of 20 studies that reported outcomes on falls rate found a significant reduction. Seventeen out of 23 studies with outcomes on fall risk factors concluded a significant improvement. Five studies found no significant differences in falls incidence, and 5 studies found no significant differences in fall risks. One study reported worsened outcomes, including poorer balance.
Although results are inconclusive, SI, MI, and MCI involving exercises may prevent falls. Vitamin D supplementation may be beneficial alongside exercise; however, whether vitamin D use consistently reduces falls incidence or fall risks remains uncertain. Exercises that are individually tailored to participants' capabilities and risks may be the most effective falls prevention interventions. Implementation may reduce medical costs and improve quality of life for older adults who are community-dwelling or are living in long-term care facilities.
确定单一干预措施(SI)、多因素干预措施(MI)或包括维生素 D 补充剂的多种成分干预措施(MCI)是否可以预防居住在社区或长期护理机构中的老年人发生跌倒和跌倒风险因素。
系统评价。
在 2015 年至 2019 年的发表年份限制和英语语言限制下,对 PubMed、Scopus、MEDLINE 和 Cochrane 进行了搜索。在重复删除和标题与摘要筛选后,2 位作者根据纳入标准独立确定了合格的研究。评估了偏倚风险和证据质量。
在对 855 条引用和 129 篇全文文章的标题和摘要进行筛选后,共纳入了 34 项研究。从 5 项 MI 研究、1 项 MCI 研究和 7 项 SI 研究中提取了 2232 名参与者的 13 项随机对照试验和临床试验以及 21 项系统评价(评估 SI、MI、MCI 或全部),用于定性综合分析。20 项报告跌倒率结果的研究中有 15 项发现跌倒率显著降低。23 项有跌倒风险因素结果的研究中有 17 项得出了显著改善的结论。5 项研究发现跌倒发生率无显著差异,5 项研究发现跌倒风险无显著差异。一项研究报告了较差的结果,包括较差的平衡。
尽管结果尚无定论,但涉及运动的 SI、MI 和 MCI 可能预防跌倒。维生素 D 补充剂与运动相结合可能有益;然而,维生素 D 的使用是否能持续降低跌倒发生率或跌倒风险仍不确定。针对参与者的能力和风险量身定制的运动可能是最有效的跌倒预防干预措施。实施这些干预措施可能会降低居住在社区或长期护理机构中的老年人的医疗费用并提高他们的生活质量。