Department of Obstetrics and Gynaecology, Dr Cipto Mangunkusumo Hospital, Central Jakarta, Indonesia
Faculty of Medicine, Universitas Indonesia, Central Jakarta, Indonesia.
BMJ Case Rep. 2020 Jul 9;13(7):e234757. doi: 10.1136/bcr-2020-234757.
Ovarian fibrosarcoma is an extremely rare tumour with no universally accepted guidelines for treatment. We present a 46-year-old nulliparous woman with ovarian fibrosarcoma who mainly presented with a painful abdominal enlargement. Optimal debulking surgery was performed, and a specimen of the tumour was examined. A frozen section examined during surgery revealed spindle cell morphology, raising the suspicion of ovarian fibrosarcoma, which was later confirmed by immunohistochemistry staining. Our patient refused to undergo chemotherapy and died 3 months after surgery due to tumour recurrence. Although no clear consensus exists for administering chemotherapy for fibrosarcoma, some published case reports have shown a lower chance of recurrence and better prognosis in patients who undergo chemotherapy compared with our patient.
卵巢纤维肉瘤是一种极其罕见的肿瘤，目前尚无普遍接受的治疗指南。我们报告了一例 46 岁的未产妇，主要表现为腹痛性腹部增大。进行了最佳的肿瘤细胞减灭术，并对肿瘤标本进行了检查。术中冷冻切片检查显示梭形细胞形态，提示卵巢纤维肉瘤，随后通过免疫组织化学染色得到证实。我们的患者拒绝接受化疗，术后 3 个月因肿瘤复发死亡。虽然对于纤维肉瘤是否进行化疗尚未达成明确共识，但一些已发表的病例报告显示，与我们的患者相比，接受化疗的患者复发机会更低，预后更好。
