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46 岁女性在接受最佳减瘤手术后迅速复发卵巢纤维肉瘤。

Rapidly recurring ovarian fibrosarcoma after optimal debulking surgery in a 46-year-old woman.

机构信息

Department of Obstetrics and Gynaecology, Dr Cipto Mangunkusumo Hospital, Central Jakarta, Indonesia

Faculty of Medicine, Universitas Indonesia, Central Jakarta, Indonesia.

出版信息

BMJ Case Rep. 2020 Jul 9;13(7):e234757. doi: 10.1136/bcr-2020-234757.

Abstract

Ovarian fibrosarcoma is an extremely rare tumour with no universally accepted guidelines for treatment. We present a 46-year-old nulliparous woman with ovarian fibrosarcoma who mainly presented with a painful abdominal enlargement. Optimal debulking surgery was performed, and a specimen of the tumour was examined. A frozen section examined during surgery revealed spindle cell morphology, raising the suspicion of ovarian fibrosarcoma, which was later confirmed by immunohistochemistry staining. Our patient refused to undergo chemotherapy and died 3 months after surgery due to tumour recurrence. Although no clear consensus exists for administering chemotherapy for fibrosarcoma, some published case reports have shown a lower chance of recurrence and better prognosis in patients who undergo chemotherapy compared with our patient.

摘要

卵巢纤维肉瘤是一种极其罕见的肿瘤,目前尚无普遍接受的治疗指南。我们报告了一例 46 岁的未产妇,主要表现为腹痛性腹部增大。进行了最佳的肿瘤细胞减灭术,并对肿瘤标本进行了检查。术中冷冻切片检查显示梭形细胞形态,提示卵巢纤维肉瘤,随后通过免疫组织化学染色得到证实。我们的患者拒绝接受化疗,术后 3 个月因肿瘤复发死亡。虽然对于纤维肉瘤是否进行化疗尚未达成明确共识,但一些已发表的病例报告显示,与我们的患者相比,接受化疗的患者复发机会更低,预后更好。

相似文献

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Ovarian fibrosarcoma with long-term survival: a case report.卵巢纤维肉瘤伴长期生存:一例报告
Int J Gynecol Cancer. 2001 Jul-Aug;11(4):331-3. doi: 10.1046/j.1525-1438.2001.011004331.x.

本文引用的文献

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Sarcomas with spindle cell morphology.具有梭形细胞形态的肉瘤。
Semin Oncol. 2009 Aug;36(4):324-37. doi: 10.1053/j.seminoncol.2009.06.007.

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