First Affiliated Hospital of Wenzhou Medical University, Wenzhou City, Zhejiang Province, China.
Wenzhou Medical University, Wenzhou City, Zhejiang Province, China.
Eur Arch Otorhinolaryngol. 2021 Apr;278(4):925-932. doi: 10.1007/s00405-020-06132-2. Epub 2020 Jul 9.
This meta-analysis is aimed to review and analyze all available data of intraoperative and postoperative results of endoscopic and microscopic stapes surgery.
According to the PRISMA statements checklist, this systematic review and meta-analysis were designed. Data were extracted from public databases, such as PubMed, Cochrane, Web of Science, and more. The quality of studies was evaluated using the MINORS scale. Odds ratios (ORs) and 95% CIs were estimated for binary outcome data, while the mean differences and 95% CIs were estimated for continuous data. I and χ tests were used to quantify statistical heterogeneity. If more than ten studies were included in each analysis, funnel plot would be performed to analysis publication bias.
Twelve studies with 620 patients were included in this meta-analysis. Primary outcomes collected in this meta-analysis included average postoperative auditory gain (APAG), postoperative air-bone gap (ABG), the rate of chorda tympani handling and bone curettage, which all showed a statistically significant difference in favor of endoscopy. While only secondary outcomes about postoperative pain and dysgeusia demonstrated a significantly reduced incidence. Furthermore, there was not any statistically significant difference on postoperative dizziness and average operative time between endoscopy and microscopy.
Although there is a need for high-quality pooled data in the future, a consistently superior effect of the endoscopic group was still shown in terms of total effectiveness, when compared to the microscopic group. We have reasons to support the application of endoscopy in stapes surgery. The future of ESS, we believe, is blazing bright.
本荟萃分析旨在回顾和分析所有可用的内镜和显微镜镫骨手术术中及术后结果数据。
根据 PRISMA 声明检查表,设计了本系统评价和荟萃分析。从公共数据库(如 PubMed、Cochrane、Web of Science 等)中提取数据。使用 MINORS 量表评估研究质量。对二项结局数据估计比值比(OR)和 95%置信区间(CI),对连续数据估计均值差和 95%CI。使用 I 2 和 χ 2 检验来量化统计异质性。如果每个分析中包含超过十项研究,则进行漏斗图分析以评估发表偏倚。
本荟萃分析纳入了 12 项研究共 620 例患者。荟萃分析中收集的主要结局包括平均术后听力增益(APAG)、术后气骨导差(ABG)、处理鼓索神经和骨刮除的比率,所有这些结局都倾向于内镜。而仅术后疼痛和味觉障碍的次要结局显示出显著降低的发生率。此外,内镜组和显微镜组在术后头晕和平均手术时间方面没有统计学上的显著差异。
尽管未来需要高质量的汇总数据,但与显微镜组相比,内镜组在总体疗效方面仍显示出一致的优势。我们有理由支持在内镜镫骨手术中的应用。我们相信,ESS 的未来是光明的。