Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York.
Otol Neurotol. 2019 Sep;40(8):983-993. doi: 10.1097/MAO.0000000000002353.
This meta-analysis compares the efficacy and safety of endoscopic and microscopic approaches to tympanoplasty and stapes surgery, two common middle ear procedures.
A comprehensive electronic search of PubMed/MEDLINE, Scopus, Web of Science, and Cochrane Library was conducted for studies published from the year 1960 through June 2018. Article selection and screening proceeded according to the strategies outlined in the standard Preferred Reporting Items for Systematic Reviews and Meta-analysis statement.
Studies were assessed for quality using the Newcastle-Ottawa Scale and the Jadad scale depending on the presence of randomization. Bias was analyzed using funnel plots. For each outcome measure, a forest plot was generated and a pooled relative risk or risk difference was calculated to assess significance.
Twenty-one studies met the inclusion criteria, 16 tympanoplasty (1,323 ears) and 5 stapes surgery (283 ears). The nonrandomized studies scored moderately well but the randomized studies were of low quality with respect to the Newcastle-Ottawa Scale and the Jadad Scale, respectively. With respect to tympanoplasty, statistical analysis demonstrated that the endoscopic approach had significantly lower canalplasty rates, better cosmetic outcomes, and shorter operative times. Furthermore, endoscopic compared to microscopic methods were similar in terms of audiological outcome, graft success rate, and complication rate. Among stapes surgeries, the endoscopic approach demonstrated a significantly decreased incidence of postoperative pain and chorda tympani injury but was similar to the microscopic approach with respect to audiological outcome, postoperative dizziness, and operative time.
Though the merits of endoscopic techniques are becoming more well known, there are still concerns regarding their efficacy and safety. An analysis of the current literature suggests that audiological, functional, and safety outcomes are similar, if not superior, for the endoscopic approach to both tympanoplasty and stapes surgery compared to the microscopic approach. With respect to tympanoplasty, patients undergoing the endoscopic approach had lower canalplasty rates, better cosmetic outcomes, and shorter operative times. Among stapes surgeries, patients in the endoscopic group had a lower incidence of postoperative pain and injury to the chorda tympani. This meta-analysis of the current evidence supports the use of endoscopic techniques for tympanoplasty and stapes surgery.
本荟萃分析比较了内镜和显微镜方法在鼓膜成形术和镫骨手术(两种常见的中耳手术)中的疗效和安全性。
对 1960 年至 2018 年 6 月期间发表的研究进行了全面的电子搜索,包括 PubMed/MEDLINE、Scopus、Web of Science 和 Cochrane Library。根据系统评价和荟萃分析标准报告的策略,进行了文章选择和筛选。
根据是否存在随机分组,使用纽卡斯尔-渥太华量表和 Jadad 量表评估研究质量。使用漏斗图分析偏倚。对于每个结局指标,生成森林图并计算合并相对风险或风险差以评估显著性。
21 项研究符合纳入标准,其中 16 项为鼓膜成形术(1323 耳),5 项为镫骨手术(283 耳)。非随机研究的评分中等,但随机研究在纽卡斯尔-渥太华量表和 Jadad 量表方面的质量较低。关于鼓膜成形术,统计分析表明,内镜方法的耳道成形术率较低,美容效果较好,手术时间较短。此外,内镜方法与显微镜方法在听力结果、移植物成功率和并发症发生率方面相似。对于镫骨手术,内镜方法术后疼痛和鼓索神经损伤的发生率显著降低,但与显微镜方法在听力结果、术后头晕和手术时间方面相似。
尽管内镜技术的优点越来越为人所知,但人们仍对其疗效和安全性存在担忧。对当前文献的分析表明,与显微镜方法相比,内镜方法在鼓膜成形术和镫骨手术中,在听力、功能和安全性方面的结果相似,甚至更优。对于鼓膜成形术,接受内镜方法的患者的耳道成形术率较低,美容效果较好,手术时间较短。对于镫骨手术,内镜组患者术后疼痛和鼓索神经损伤的发生率较低。本荟萃分析当前证据支持在鼓膜成形术和镫骨手术中使用内镜技术。