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使用 Halcyon 直线加速器对容积调强弧形治疗进行双层多叶准直器的计划复杂性量化。

Plan complexity quantification of dual-layer multi-leaf collimator for volumetric modulated arc therapy with Halcyon linac.

机构信息

Department of Medical Physics, Graduate School of Medical Sciences, Kindai University, 377-2 Onohigashi, Osakasayama, Osaka, 5898511, Japan.

Department of Radiology, Kindai University Hospital, 377-2 Onohigashi, Osakasayama, Osaka, 5898511, Japan.

出版信息

Phys Eng Sci Med. 2020 Sep;43(3):947-957. doi: 10.1007/s13246-020-00891-2. Epub 2020 Jul 9.

Abstract

This study characterized the plan complexity of the dual-layer multi-leaf collimator (MLC) performance for volumetric modulated arc therapy (VMAT) in Halcyon. Plan complexity metrics were computed independently for each MLC layer (proximal and distal): modulation complexity score (MCS), plan averaged beam area, irregularity, and modulation (PA, PI, and PM) were obtained. These were investigated when weighted by proportions of the effective proximal MLC and distal MLC (MCS, PA, PI, and PM). Conventional plan complexity metrics for the effective 5.0 mm resolution MLC (MCS, PA, PI, PM), small aperture score (SAS), effective distal MLC score (EDS), and MU were also evaluated. Forty-five consecutive VMAT plans were analyzed retrospectively for treatment sites of the prostate, head and neck (HN), and other parts. The mean values of the metrics for proximal MLC and distal MLC were 0.310 and 0.245 (MCS), 71.09 cm and 55.92 cm (PA), 6.24 and 10.19 (PI), and 0.593 and 0.645 (PM), respectively. The degree of plan complexity in the distal MLC was larger than in the proximal MLC. The percentage of the effective distal MLC was higher than that of the proximal MLC (mean EDS = 0.555). The MCS, PA, PI, and PM showed significant differences between the prostate and HN groups like the PA, PI, and PM; however, the MCS did not. Additionally, the MCS correlated with MU and PM, while the MCS correlated with SAS and PA. The plan complexity for each MLC layer and subsequently combining these complexities might be useful to better understand the dual-layer MLC performance.

摘要

本研究对 Halcyon 中容积调制弧形治疗(VMAT)的双层多叶准直器(MLC)性能的计划复杂性进行了描述。分别为每个 MLC 层(近端和远端)计算了调制复杂性评分(MCS)、计划平均射束面积、不规则性和调制(PA、PI 和 PM)。当按有效近端 MLC 和远端 MLC 的比例加权时,研究了这些参数(MCS、PA、PI 和 PM)。还评估了有效 5.0mm 分辨率 MLC 的常规计划复杂性参数(MCS、PA、PI、PM)、小孔径评分(SAS)、有效远端 MLC 评分(EDS)和 MU。回顾性分析了 45 例连续 VMAT 计划,这些计划的治疗部位为前列腺、头颈部(HN)和其他部位。近端 MLC 和远端 MLC 的平均指标值分别为 0.310 和 0.245(MCS)、71.09cm 和 55.92cm(PA)、6.24 和 10.19(PI)和 0.593 和 0.645(PM)。远端 MLC 的计划复杂性程度大于近端 MLC。有效远端 MLC 的百分比高于近端 MLC(平均 EDS=0.555)。MCS、PA、PI 和 PM 与前列腺和 HN 组之间存在显著差异,如 PA、PI 和 PM;然而,MCS 没有。此外,MCS 与 MU 和 PM 相关,而 MCS 与 SAS 和 PA 相关。每个 MLC 层的计划复杂性以及随后组合这些复杂性可能有助于更好地理解双层 MLC 性能。

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