Channer K S, O'Connor S, Britton S, Walbridge D, Rees J R
Department of Cardiology, Bristol Royal Infirmary.
J R Soc Med. 1988 Nov;81(11):629-32. doi: 10.1177/014107688808101105.
Thirty-six patients with angina were investigated by treadmill exercise testing and coronary angiography prior to coronary artery surgery. Severity of angina was judged by interview and self-assessment visual analogue scale and all patients were psychiatrically assessed. Further physical and psychiatric assessments were made at 3 and 6 months postoperatively. Eleven patients (31%) had significant psychiatric morbidity preoperatively and these had worse symptom scores and exercise tolerance compared with non-psychiatric cases, despite equivalent coronary angiographic findings and left ventricular function. Post-operatively, exercise tolerance improved equally in both groups but psychiatric cases remained significantly more symptomatic. Psychiatric morbidity remained unchanged throughout the study. We conclude that almost one third of patients with severe angina have psychiatric morbidity which is associated with a poor symptomatic response to coronary artery surgery, despite objective improvement in exercise tolerance. Ways of improving the symptomatic response to surgery in patients with coexisting psychiatric morbidity should be studied.
36例心绞痛患者在冠状动脉手术前接受了平板运动试验和冠状动脉造影检查。通过访谈和自我评估视觉模拟量表判断心绞痛的严重程度,并对所有患者进行了精神评估。术后3个月和6个月进行了进一步的身体和精神评估。11例患者(31%)术前有明显的精神疾病,尽管冠状动脉造影结果和左心室功能相当,但与非精神疾病患者相比,这些患者的症状评分和运动耐量更差。术后,两组患者的运动耐量均有同等程度的改善,但有精神疾病的患者症状仍明显更多。在整个研究过程中,精神疾病发病率保持不变。我们得出结论,尽管运动耐量有客观改善,但近三分之一的重度心绞痛患者存在精神疾病,这与冠状动脉手术的症状反应不佳有关。应研究改善合并精神疾病患者手术症状反应的方法。