Department of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing, China.
Beijing Key Laboratory of Sports Injuries, Institute of Sports Medicine, Peking University Third Hospital, Beijing, China.
Comput Methods Biomech Biomed Engin. 2020 Nov;23(14):1102-1108. doi: 10.1080/10255842.2020.1789119. Epub 2020 Jul 10.
The normalcy index (NI) has been implemented by several studies as a simple index for quantitatively analyzing diffident gait abnormalities, such as children with cerebral palsy and idiopathic toe-walkers. However, whether the NI can be used in anterior cruciate ligament (ACL) deficiency with different types of meniscus injuries or not, has not been reported yet. In this study, 25 patients who combined different types of ACL and meniscus injuries were evaluated by the NI analysis. 12 healthy subjects were used to define the normal range of NI. The result showed that NI values of patients were significantly larger than the control group (P < 0.05). Meanwhile, the tendency of increasing NI values associated with increasing pathology were significant with only 5 subjects in the smallest group (Jonkheere-Terpsta test: P < 0.001). These results indicated that the NI was a concise yet effective tool to evaluate combined ACL and meniscus injury patients. Increasing severity degree of meniscus tears in ACL rupture patients is corresponded to increasing NI values. It also demonstrates that the proposed NI can be applied as a robustness factor to detect the discrepancy between healthy and patient subjects clinically, and has the potential in the quantitative evaluation of pre- or post-surgery and rehabilitation.
正常指数(NI)已被多项研究用作分析不同步态异常的简单指标,例如脑瘫和特发性足尖行走儿童。然而,NI 是否可用于前交叉韧带(ACL)缺失伴不同类型半月板损伤,尚未有报道。在这项研究中,25 名合并不同类型 ACL 和半月板损伤的患者接受了 NI 分析评估。12 名健康受试者被用于定义 NI 的正常范围。结果表明,患者的 NI 值明显大于对照组(P<0.05)。同时,与病理学程度增加相关的 NI 值增加趋势具有显著性,最小组仅 5 名受试者(Jonkheere-Terpstra 检验:P<0.001)。这些结果表明,NI 是一种简洁有效的工具,可用于评估合并 ACL 和半月板损伤的患者。ACL 断裂患者半月板撕裂的严重程度增加与 NI 值增加相对应。这也表明,所提出的 NI 可作为一种稳健性因素,用于临床上检测健康受试者和患者之间的差异,并且具有在术前、术后和康复期间进行定量评估的潜力。