Rennie J A, MacLeod M M, Reynolds P N, El-Ghobarey A F
Curr Med Res Opin. 1977;4(8):580-3. doi: 10.1185/03007997709115273.
A double-blind crossover study was conducted in 15 patients with classical definite rheumatoid arthritis to compare the effect of sodium meclofenamate (300 mg daily) with placebo and indomethacin (100 mg daily). Each treatment was administered for 1 week to patients assigned at random to treatment sequences. The active drugs were shown to be significantly superior to placebo. Sodium meclofenamate alone reduced the articular index. Patient preference, however, was in favour of indomethacin.
对15例典型确诊类风湿性关节炎患者进行了一项双盲交叉研究，以比较甲氯芬那酸钠（每日300毫克）与安慰剂和吲哚美辛（每日100毫克）的效果。将患者随机分配到治疗序列中，每种治疗给药1周。结果显示活性药物明显优于安慰剂。单独使用甲氯芬那酸钠可降低关节指数。然而，患者更倾向于吲哚美辛。
