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采用三维打印近端趾骨假体及跖趾关节置换术治疗第五趾骨巨细胞瘤:首例病例报告

Three-dimensional printed, proximal phalangeal prosthesis with metatarsophalangeal joint arthroplasty for the treatment of a giant cell tumor of the fifth toe: The first case report.

作者信息

Chandhanayingyong Chandhanarat, Srikong Korakod, Puncreobutr Chedtha, Lohwongwatana Boonrat, Phimolsarnti Rapin, Chuckpaiwong Bavornrit

机构信息

Division of Musculoskeletal Oncology, Department of Orthopaedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Biomechanic Research Center, Meticuly Co Ltd., Chulalongkorn University, Bangkok, Thailand.

出版信息

Int J Surg Case Rep. 2020;73:84-89. doi: 10.1016/j.ijscr.2020.06.069. Epub 2020 Jun 22.

Abstract

INTRODUCTION

The majority of patients with bone sarcoma or an aggressive benign tumor of the toe can be successfully treated by amputation. However, limb-salvage surgery for toe tumors remains challenging.

PRESENTATION OF CASE

A 26-year-old female presented with an enlarging mass on her right 5th toe. Imaging studies revealed an expansile osteolytic, destructive lesion of the proximal phalanx of the 5th toe with metatarsophalangeal (MTP) joint invasion. A biopsy specimen confirmed a grade 1, giant cell tumor of the bone. An en bloc resection of the proximal phalanx was performed, and the defect was reconstructed with a patient-matched, three-dimensional, printed titanium proximal phalanx endoprosthesis with an MTP joint extension. The postoperative course was uneventful. The patient has walked with full weight-bearing since early postoperatively. No local recurrence or metastases were evident. However, scar formation occurred after two years, causing an overriding toe deformity.

DISCUSSION

This case represents the first use of a toe prosthesis with MTP joint reconstruction. The complex MTP structure with a preserved metatarsal head facilitates the effort to mimic normal weight-bearing.

CONCLUSION

A three-dimensional printed prosthesis of the 5th toe is a viable alternative to a bone graft or amputation. However, to avoid stiffness and complications, further study is needed to improve the prosthesis design.

摘要

引言

大多数骨肉瘤患者或侵袭性良性脚趾肿瘤患者可通过截肢成功治疗。然而,脚趾肿瘤的保肢手术仍然具有挑战性。

病例介绍

一名26岁女性因右足第5趾肿物增大就诊。影像学检查显示第5趾近节趾骨有一个膨胀性溶骨性、破坏性病变,累及跖趾关节。活检标本证实为1级骨巨细胞瘤。对近节趾骨进行了整块切除,并用与患者匹配的三维打印钛制近节趾骨假体及跖趾关节延长部分重建了缺损。术后过程顺利。患者术后早期即可完全负重行走。未见局部复发或转移。然而,两年后出现瘢痕形成,导致脚趾重叠畸形。

讨论

本病例代表首次使用带跖趾关节重建的脚趾假体。保留跖骨头的复杂跖趾结构有助于模拟正常负重。

结论

第5趾三维打印假体是骨移植或截肢的可行替代方案。然而,为避免僵硬和并发症,需要进一步研究以改进假体设计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/339e/7341039/8f06118e51cb/gr1.jpg

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