Department of Otolaryngology-Head & Neck Surgery, Medical University of South Carolina, Charleston.
Hypertension and Vascular Research Center, Wake Forest School of Medicine, Winston-Salem, NC.
Am J Speech Lang Pathol. 2020 Jul 10;29(2S):945-955. doi: 10.1044/2019_AJSLP-19-00067.
Purpose Diagnostic precision and prolonged testing before, during, and after deglutition is lacking across the age spectrum. Conventional clinical evaluation and radiologic methods are widely used but are reliant on human perception, carrying the risk of subjectivity. High-resolution manometry (HRM) is an emerging clinical and research tool and has the capability to objectively measure the dynamics, kinetics, regulatory, and correlation aspects of deglutition. Method We review the basics of manometry and the methods, metrics, and applications of this technology across the age spectrum. The goal is to aid in the translation of HRM from research tool to clinical use by the speech-language pathologist in the development of better global plans to understand normal and abnormal deglutition. Results HRM is an easily adaptable precise diagnostic tool that can be used to examine deglutition phases and abnormalities across the age spectrum from neonates to nonagenarians and can be a valuable adjunct to specialty evaluation of persistent deglutition disorders. Conclusion New opportunities will emerge upon further research for larger-scale translation once normative data and recognition of biomarkers of abnormality are ascertained.
目的 在整个年龄范围内,吞咽前、吞咽中和吞咽后的诊断精度和延长测试都缺乏。传统的临床评估和放射学方法被广泛应用,但依赖于人类的感知,存在主观性的风险。高分辨率测压(HRM)是一种新兴的临床和研究工具,具有客观测量吞咽动力学、动力学、调节和相关性方面的能力。
方法 我们回顾了测压的基础知识,以及这项技术在整个年龄范围内的方法、指标和应用。目的是通过言语病理学家将 HRM 从研究工具转化为临床应用,帮助制定更好的全球计划,以理解正常和异常吞咽。
结果 HRM 是一种适应性强的精确诊断工具,可用于检查从新生儿到 90 岁以上的各个年龄段的吞咽阶段和异常情况,并且可以作为对持续性吞咽障碍进行专业评估的有价值的辅助手段。
结论 一旦确定了正常数据和异常生物标志物的识别,进一步的研究将为更大规模的转化带来新的机会。