Graff Stephanie L, Holder Jared M, Sears Lindsay E, Kurbegov Dax
Sarah Cannon Cancer Institute at HCA Midwest Health, Overland Park, KS.
Sarah Cannon Research Institute, Nashville, TN.
JCO Oncol Pract. 2020 Dec;16(12):e1481-e1488. doi: 10.1200/JOP.19.00552. Epub 2020 Jul 10.
Genetic counseling and testing (GC/T) for breast cancer-associated genetic mutations are important components in the appropriate management of newly diagnosed breast cancer. We initiated pathways to help appropriately select patients who meet criteria for GC/T referral (GC/T-R) across the Sarah Cannon Cancer Institute Network. This study evaluated physician pathway training as a means to improve access to GC/T-R.
In this retrospective, observational study, we collected data from 7 regions across 6 states, identifying 3,113 patients eligible for GC/T. Patients were divided into 3 defined cohorts: patients treated before implementation of pathways (n = 988), patients treated by non-pathway physicians after pathways were established (n = 1,094), and patients treated by pathway-trained physicians (n = 1,031). Pathways were established in March 2016. Nurse navigators documented eligible patients who were referred for GC/T within a care coordination software system.
Eligible patients were referred for GC/T 71.77% of the time if treated on pathways and only 36.47% of the time if treated off pathways. On-pathway patients eligible for GC/T also received testing referral at a higher rate than pre-pathway patients (21.36%).
After implementation of pathways and appropriate training of physicians on those pathways, GC/T-R among appropriate patients significantly improved. Pathway training represents a potential solution to improve GC/T-R among patients with breast cancer.
对乳腺癌相关基因突变进行遗传咨询和检测(GC/T)是新诊断乳腺癌合理管理的重要组成部分。我们启动了相关流程,以帮助在莎拉·坎农癌症研究所网络中适当选择符合GC/T转诊标准(GC/T-R)的患者。本研究评估了医生流程培训作为改善GC/T-R可及性的一种手段。
在这项回顾性观察研究中,我们收集了来自6个州7个地区的数据,确定了3113名符合GC/T条件的患者。患者被分为3个明确的队列:在流程实施前接受治疗的患者(n = 988)、流程建立后由非流程医生治疗的患者(n = 1094)以及由接受流程培训的医生治疗的患者(n = 1031)。流程于2016年3月建立。护士导航员在护理协调软件系统中记录了被转诊进行GC/T的符合条件的患者。
符合条件的患者如果按照流程接受治疗,被转诊进行GC/T的时间占比为71.77%,而如果未按照流程接受治疗,这一比例仅为36.47%。符合GC/T条件的流程内患者接受检测转诊的比例也高于流程前患者(21.36%)。
在实施流程并对医生进行适当的流程培训后,合适患者中的GC/T-R显著改善。流程培训是提高乳腺癌患者GC/T-R的一个潜在解决方案。