Sorbonne Université, Endoscopy Unit, AP-HP, Hôpital Saint-Antoine, 75012 Paris, France.
Sorbonne Université, Pathology Department, AP-HP, Hôpital Saint-Antoine, 75012 Paris, France.
Clin Res Hepatol Gastroenterol. 2021 May;45(3):101484. doi: 10.1016/j.clinre.2020.06.010. Epub 2020 Jul 7.
A serrated polyposis syndrome was diagnosed in a 26-year-old female presenting with gastrointestinal symptoms. Screening for other lesions of the gastrointestinal tract showed a serpiginous looking papilla, described as possibly dysplastic. Histological analysis of biopsies showed a serrated lesion. This case describes the first known association between a duodenal serrated lesion and serrated polyposis syndrome. Upper GI screening is probably of little interest in this setting. In patients with upper GI serrated lesions, we recommend screening colonoscopy.
在一位 26 岁的女性出现胃肠道症状时,诊断出锯齿状息肉综合征。对胃肠道其他病变的筛查显示出一种蜿蜒状的乳头,被描述为可能发育不良。活检的组织学分析显示出锯齿状病变。该病例描述了首例已知的十二指肠锯齿状病变与锯齿状息肉综合征之间的关联。在上消化道存在锯齿状病变的情况下,进行上消化道筛查可能意义不大。对于上消化道存在锯齿状病变的患者,我们建议进行结肠镜筛查。