Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow region, Russia.
Bull Exp Biol Med. 2020 Jun;169(2):266-269. doi: 10.1007/s10517-020-04865-y. Epub 2020 Jul 10.
Mauthner neurons in goldfish fry were studied by the methods of light and electron microscopy. The structure and volume of individual dendrites as well as the structure of axodendritic synapses were examined using virtual images of neurons formed from serial 3-μ sections. In short-time (5 h) experiments with application of dopamine, β-amyloid fragment (25-35), and long-term sensory stimulation affecting afferent inputs to Mauthner neurons, the dendrites were larger than the same dendrites under the same conditions without dopamine application. Application of dopamine induced no pathological changes in the structure of axodendritic chemical and electric synapses containing desmosome-like contacts.
采用光镜和电镜方法研究了金鱼幼鱼的 Mauthner 神经元。通过对连续 3μm 切片形成的神经元虚拟图像，研究了单个树突的结构和体积以及轴突树突突触的结构。在多巴胺、β-淀粉样片段（25-35）短期（5 小时）给药和影响 Mauthner 神经元传入输入的长期感觉刺激的实验中，与没有多巴胺给药的相同条件下相比，树突较大。多巴胺的应用未引起含有桥粒样连接的轴突树突化学和电突触的结构发生病理性变化。
