College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong Province, 266109, PR China.
College of Animal Science and Technology, Jilin Agricultural University, Changchun, Jilin Province, 130118, PR China.
Prev Vet Med. 2020 Sep;182:105083. doi: 10.1016/j.prevetmed.2020.105083. Epub 2020 Jul 1.
Haemophilus parasuis, a gram-negative bacterium as an early commensal colonizer in the upper respiratory tract of weaning pigs (Sus scrofa), is one of the most important bacterial pathogens affecting pig populations. It is the causative agent of Glässer's disease, causing systemic infection and polyserositis, meningitis, and arthritis. H. parasuis infection can result in high mortality and morbidity with, the significant economic losses for pig producers. To estimate the overall disease prevalence of H. parasuis in pigs from China, we performed a meta-analysis using five bibliographical databases: PubMed, ScienceDirect, CNKI, Wanfang, and VIP Chinese Journal Databases. A total of 41 articles published between 2005 and 2019, fulfilled the final inclusion criteria. The overall prevalence of H. parasuis in pigs in China was 27.8 % with the highest prevalence between 2011 and 2015 (41.0 %). In terms of pig age, the point estimate of H. parasuis prevalence was higher in suckling piglets (29.2 %) compared with that for other pig ages. The prevalence in the serum subgroup (29.8 %) was higher than that in the nasal swab subgroup (12.5 %). The results of the present meta-analysis showed that H. parasuis infection was common in pig populations in China; therefore, effective control measures are necessary to reduce this threat to pig populations.
副猪嗜血杆菌是一种革兰氏阴性菌，作为断奶仔猪上呼吸道的早期共生定植菌（Sus scrofa），是影响猪群的最重要的细菌病原体之一。它是导致格拉泽氏病的病原体，引起全身感染和多发性浆膜炎、脑膜炎和关节炎。副猪嗜血杆菌感染可导致高死亡率和发病率，给养猪户造成重大经济损失。为了估计中国猪群中副猪嗜血杆菌的总体疾病流行率，我们使用五个文献数据库（PubMed、ScienceDirect、CNKI、万方和 VIP 中文期刊数据库）进行了荟萃分析。共有 2005 年至 2019 年期间发表的 41 篇文章符合最终纳入标准。中国猪群中副猪嗜血杆菌的总体流行率为 27.8%，2011 年至 2015 年期间的流行率最高（41.0%）。按猪年龄划分，哺乳仔猪的副猪嗜血杆菌流行率估计值（29.2%）高于其他猪年龄组。血清亚组（29.8%）的流行率高于鼻拭子亚组（12.5%）。本荟萃分析的结果表明，副猪嗜血杆菌感染在中国猪群中很常见；因此，有必要采取有效的控制措施来降低这种对猪群的威胁。
