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Identification of a multiresistant mosaic plasmid carrying a new segment of IS1216E-flanked optrA with integrated Tn551-ermB element in linezolid-resistant Enterococcus faecalis human isolate.

作者信息

Iimura Masaki, Hayashi Wataru, Arai Eriko, Natori Tatsuya, Horiuchi Kazuki, Matsumoto Go, Tanaka Hayato, Soga Eiji, Nagano Yukiko, Arakawa Yoshichika, Nagano Noriyuki

机构信息

Department of Health and Medical Sciences, Shinshu University Graduate School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

Department of Medical Sciences, Shinshu University Graduate School of Medicine, Science and Technology, Nagano, Japan.

出版信息

J Glob Antimicrob Resist. 2020 Sep;22:697-699. doi: 10.1016/j.jgar.2020.06.030. Epub 2020 Jul 9.

DOI:10.1016/j.jgar.2020.06.030
PMID:32653723
Abstract
摘要

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Identification of a multiresistant mosaic plasmid carrying a new segment of IS1216E-flanked optrA with integrated Tn551-ermB element in linezolid-resistant Enterococcus faecalis human isolate.在耐利奈唑胺的粪肠球菌临床分离株中鉴定出一种多重耐药镶嵌质粒，该质粒携带一段新的由IS1216E侧翼optrA组成的片段，并整合了Tn551-ermB元件。
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Interregional spread in Spain of linezolid-resistant Enterococcus spp. isolates carrying the optrA and poxtA genes.西班牙耐林可霉素肠球菌属分离株中携带 optrA 和 poxtA 基因的区际传播。
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Detection of transferable oxazolidinone resistance determinants in Enterococcus faecalis and Enterococcus faecium of swine origin in Sichuan Province, China.中国四川省猪源粪肠球菌和屎肠球菌中可转移的恶唑烷酮类耐药决定因子的检测。
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A novel gene, optrA, that confers transferable resistance to oxazolidinones and phenicols and its presence in Enterococcus faecalis and Enterococcus faecium of human and animal origin.一种赋予对恶唑烷酮类和酚类药物可转移抗性的新基因optrA，以及它在人和动物源粪肠球菌和屎肠球菌中的存在情况。
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