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神经胶质瘤生物技术的最新进展

Update on glioma biotechnology.

机构信息

Department of Neurosurgery, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA.

Department of Neurosurgery, Lenox Hill Hospital, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, USA.

出版信息

Clin Neurol Neurosurg. 2020 Aug;195:106075. doi: 10.1016/j.clineuro.2020.106075. Epub 2020 Jul 7.

DOI:10.1016/j.clineuro.2020.106075
PMID:32653731
Abstract

Neuro-oncological research is at the forefront of the rising cancer therapy market, as evidenced by its growing revenue and the multitude of clinical trials investigating innovative treatment approaches. The Feinstein Institute for Medical Research, in conjunction with the Department of Neurosurgery at Lenox Hill Hospital and the Zucker School of Medicine at Hofstra / Northwell, sponsored The Brain Tumor Biotech Summit in New York City in June 2019. The aim of the Summit was to provide a forum that encourages collaboration between cancer specialists, biotechnology and pharmaceutical industry leaders, and the investment community in order to promote innovation and advance emerging therapies for brain tumors. Areas highlighted during the Summit included immunotherapy, precision medicine, and novel applications and experimental treatments such as receptor targeting, methods for improved drug delivery, and innovative intraoperative techniques and technologies. This review synthesizes the recent breakthroughs in brain tumor research as presented at The Brain Tumor Biotech Summit.

摘要

神经肿瘤学研究处于癌症治疗市场兴起的前沿,其不断增长的收入和大量临床试验表明了这一点,这些试验正在探索创新的治疗方法。费恩斯坦医学研究所与莱诺克斯山医院神经外科以及霍夫斯特拉/北岸大学扎克医学院合作,于 2019 年 6 月在纽约市举办了脑肿瘤生物技术峰会。峰会的目的是提供一个论坛,鼓励癌症专家、生物技术和制药行业领导者以及投资界之间的合作,以促进创新并推进脑肿瘤的新兴疗法。峰会期间强调的领域包括免疫疗法、精准医学以及新型应用和实验治疗,如受体靶向、改进药物输送的方法以及创新的术中技术和技术。本文综述了在脑肿瘤生物技术峰会上展示的脑肿瘤研究的最新突破。

相似文献

1
Update on glioma biotechnology.神经胶质瘤生物技术的最新进展
Clin Neurol Neurosurg. 2020 Aug;195:106075. doi: 10.1016/j.clineuro.2020.106075. Epub 2020 Jul 7.
2
Neuro-oncology biotech industry progress report.神经肿瘤学生物技术行业进展报告。
J Neurooncol. 2016 May;128(1):175-182. doi: 10.1007/s11060-016-2087-z. Epub 2016 Feb 20.
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Industry progress report on neuro-oncology: a biotech update.神经肿瘤学行业进展报告:生物技术更新。
J Neurooncol. 2013 Apr;112(2):315-21. doi: 10.1007/s11060-012-1036-8. Epub 2013 Feb 20.
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Industry progress report on neuro-oncology: Biotech update 2013.神经肿瘤学行业进展报告:2013 年生物技术更新。
J Neurooncol. 2013 Nov;115(2):311-6. doi: 10.1007/s11060-013-1222-3. Epub 2013 Aug 16.
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The neurosurgeon as local oncologist: cellular and molecular neurosurgery in malignant glioma therapy.神经外科医生作为局部肿瘤学家:恶性胶质瘤治疗中的细胞与分子神经外科手术
Neurosurgery. 2003 Jun;52(6):1411-22; discussion 1422-4. doi: 10.1227/01.neu.0000064808.27512.cf.
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Locoregional therapies for glioma.胶质瘤的局部区域治疗。
Oncology (Williston Park). 2005 Dec;19(14):1803-10; discussion 1810, 1816-7, 1821-2.
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Immunotherapy approaches in the treatment of malignant brain tumors.恶性脑肿瘤治疗中的免疫疗法
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Novel biologic therapies for malignant gliomas. Antiangiogenesis, immunotherapy, and gene therapy.恶性胶质瘤的新型生物疗法。抗血管生成、免疫疗法和基因疗法。
Neurol Clin. 1995 Nov;13(4):827-46.
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Immunotherapy and Response Assessment in Malignant Glioma: Neuro-oncology Perspective.恶性胶质瘤的免疫治疗与疗效评估:神经肿瘤学视角
Top Magn Reson Imaging. 2020 Apr;29(2):95-102. doi: 10.1097/RMR.0000000000000233.
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[Immunotherapy in brain tumors].[脑肿瘤的免疫疗法]
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