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诺丁汉髋部骨折评分预测髋部骨折患者住院期间的活动能力、住院时间和死亡率及出院去向的能力。

The Ability of the Nottingham Hip Fracture Score to Predict Mobility, Length of Stay and Mortality in Hospital, and Discharge Destination in Patients Admitted with a Hip Fracture.

机构信息

Department of Orthogeriatrics, Ashford and St Peter's NHS Foundation Trust, Guildford Road, Chertsey, Surrey, KT16 0PZ, UK.

Department of Cardiology, Ashford and St Peter's NHS Foundation Trust, Guildford Road, Chertsey, Surrey, KT16 0PZ, UK.

出版信息

Calcif Tissue Int. 2020 Oct;107(4):319-326. doi: 10.1007/s00223-020-00722-2. Epub 2020 Jul 11.

Abstract

The Nottingham Hip Fracture Score (NHFS) has been developed for predicting 30-day and 1-year mortality after hip fracture. We hypothesise that NHFS may also predict other adverse events. Data from 666 patients (190 men, 476 women), aged 60.2-103.4 years, admitted with a hip fracture to a single centre from 1/10/2015 and 7/12/2017 were analysed. The ability of NHFS to predict mobility within 1 day after surgery, length of stay (LOS) find mortality, and discharge destination was evaluated by receiver operating characteristic curves and two-graph plots. The area under the curve (95% confidence interval [CI]) for predicting mortality was 67.4% (58.4-76.4%), prolonged LOS was 59.0% (54.0-64.0%), discharge to residential/nursing care was 62.3% (54.0-71.5%), and any two of failure to mobilise, prolonged LOS or discharge to residential/nursing care was 64.8% (59.0-70.6%). NHFS thresholds at 4 and 7 corresponding to the lower and upper limits of intermediate range where sensitivity and specificity equal 90% were identified for mortality and prolonged LOS, and 4 and 6 for discharge to residential/nursing care, which were used to create three risk categories. Compared with the low risk group (NHFS = 0-4), the high risk group (NHFS = 7-10 or 6-10) had increased risk of in-patient mortality: rates = 2.0% versus 7.1%, OR (95% CI) = 3.8 (1.5-9.9), failure to mobilise within 1 day of surgery: rates = 18.9% versus 28.3%, OR = 1.7 (1.0-2.8), prolonged LOS (> 17 days): rates = 20.3% versus 33.9%, OR = 2.2 (1.3-3.3), discharge to residential/nursing care: rates = 4.5% vs 12.3%, OR = 3.0 (1.4-6.4), and any two of failure to mobilise, prolonged LOS or discharge to residential/nursing care: rates = 10.5% versus 28.6%, 3.4 (95% CI 1.9-6.0), and stayed 4.1 days (1.5-6.7 days) longer in hospital. High NHFS associates with increased risk of mortality, prolonged LOS and discharge to residential/nursing care, lending further support for its use to identify adverse events.

摘要

诺丁汉髋部骨折评分(NHFS)是用于预测髋部骨折后 30 天和 1 年死亡率的工具。我们假设 NHFS 也可以预测其他不良事件。对 2015 年 10 月 1 日至 2017 年 12 月 7 日期间因髋部骨折在单一中心入院的 666 例患者(男性 190 例,女性 476 例)的年龄为 60.2-103.4 岁的数据进行了分析。使用接收者操作特征曲线和双图评估 NHFS 预测手术后 1 天内活动能力、住院时间(LOS)和死亡率以及出院去向的能力。用于预测死亡率的曲线下面积(95%置信区间[CI])为 67.4%(58.4-76.4%),延长 LOS 为 59.0%(54.0-64.0%),出院至住宅/护理院为 62.3%(54.0-71.5%),无法移动、延长 LOS 或出院至住宅/护理院中的任意两项为 64.8%(59.0-70.6%)。在死亡率和延长 LOS 方面,分别确定了对应中值范围下限和上限的 4 和 7 分的 NHFS 阈值,以识别灵敏度和特异性均为 90%的中间范围,而在出院至住宅/护理院方面,确定了对应中间范围下限和上限的 4 和 6 分的 NHFS 阈值,以识别灵敏度和特异性均为 90%的中间范围。与低风险组(NHFS=0-4)相比,高风险组(NHFS=7-10 或 6-10)的住院死亡率风险更高:发生率分别为 2.0%和 7.1%,比值比(95%CI)为 3.8(1.5-9.9),无法在手术后 1 天内移动的比例分别为 18.9%和 28.3%,比值比为 1.7(1.0-2.8),延长 LOS(>17 天)的比例分别为 20.3%和 33.9%,比值比为 2.2(1.3-3.3),出院至住宅/护理院的比例分别为 4.5%和 12.3%,比值比为 3.0(1.4-6.4),无法移动、延长 LOS 或出院至住宅/护理院中的任意两项的比例分别为 10.5%和 28.6%,比值比为 3.4(95%CI 1.9-6.0),住院时间延长 4.1 天(1.5-6.7 天)。高 NHFS 与死亡率、延长 LOS 和出院至住宅/护理院的风险增加相关,进一步支持其用于识别不良事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f48/7497295/3ab95915bfea/223_2020_722_Fig1_HTML.jpg

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