Department of Emergency, Beijing Jishuitan Hospital, Beijing, China.
Orthop Surg. 2023 Apr;15(4):1096-1103. doi: 10.1111/os.13624. Epub 2023 Feb 15.
Although several prognostic models have been developed for patients who underwent hip fracture surgery, their preoperative performance was insufficiently validated. We aimed to verify the effectiveness of the Nottingham Hip Fracture Score (NHFS) for predicting postoperative outcomes following hip fracture surgery.
This was a single-center and retrospective analysis. A total of 702 elderly patients with hip fractures (age ≥ 65 years old) who received treatment in our hospital from June 2020 to August 2021 were selected as the research participants. They were divided into the survival group and the death group based on their survival 30 days after surgery. The multivariate logistic regression model was used to identify the independent risk factors for the 30-day mortality after surgery. The NHFS and American Society of Anaesthesiologists (ASA) grades were used to construct these models, and a receiver operating characteristic curve was plotted to assess their diagnostic significance. A correlation analysis was performed between NHFS and length of hospitalization and mobility 3 months after surgery.
There were significant differences in the age, albumin level, NHFS, and ASA grade between both groups (p < 0.05). The length of hospitalization in the death group was longer than the survival group (p < 0.05). The perioperative blood transfusion and postoperative ICU transfer rates in the death group were higher than in the survival group (p < 0.05). The death group's incidence of pulmonary infections, urinary tract infections, cardiovascular events, pressure ulcers, stress ulcers with bleeding, and intestinal obstruction was higher than the survival group (p < 0.05). The NHFS and ASA III were independent risk factors for the 30-day mortality after surgery, regardless of age and albumin level (p < 0.05). The area under the curve (AUC) of the NHFS and ASA grade for predicting the 30-day mortality after surgery was 0.791 (95% confidence interval [CI] 0.709-0.873, p < 0.05) and 0.621 (95% CI 0.477-0.764, p > 0.05), respectively. The NHFS positively correlated with hospitalization length and mobility grade 3 months after surgery (p < 0.05).
The NHFS demonstrated a better predictive performance than the ASA score for the 30-day mortality after surgery and positively correlated with the hospitalization length and postoperative activity limitation in elderly patients with hip fractures.
尽管已经开发出多种用于接受髋关节骨折手术患者的预后模型,但它们的术前表现尚未得到充分验证。我们旨在验证诺丁汉髋关节骨折评分(NHFS)对预测髋关节骨折手术后术后结局的有效性。
这是一项单中心回顾性分析。选择 2020 年 6 月至 2021 年 8 月在我院接受治疗的 702 例老年髋部骨折患者(年龄≥65 岁)作为研究对象。根据术后 30 天的生存情况,将其分为生存组和死亡组。采用多变量逻辑回归模型确定术后 30 天死亡率的独立危险因素。使用 NHFS 和美国麻醉医师协会(ASA)分级来构建这些模型,并绘制受试者工作特征曲线以评估其诊断意义。分析 NHFS 与术后 3 个月住院时间和活动能力之间的相关性。
两组间年龄、白蛋白水平、NHFS 和 ASA 分级存在显著差异(p<0.05)。死亡组的住院时间长于生存组(p<0.05)。死亡组围手术期输血和术后 ICU 转率高于生存组(p<0.05)。死亡组肺部感染、尿路感染、心血管事件、压疮、出血性应激性溃疡和肠梗阻的发生率高于生存组(p<0.05)。NHFS 和 ASA III 是术后 30 天死亡率的独立危险因素,与年龄和白蛋白水平无关(p<0.05)。NHFS 和 ASA 分级预测术后 30 天死亡率的曲线下面积(AUC)分别为 0.791(95%置信区间 0.709-0.873,p<0.05)和 0.621(95%置信区间 0.477-0.764,p>0.05)。NHFS 与术后 3 个月的住院时间和活动能力分级呈正相关(p<0.05)。
NHFS 对老年髋部骨折患者术后 30 天死亡率的预测效果优于 ASA 评分,并与住院时间和术后活动受限呈正相关。