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Outer-membrane permeability to beta-lactam antibiotics in Yersinia enterocolitica.

作者信息

Brzostek K, Hrebenda J

机构信息

Institute of Microbiology, Warsaw University, Poland.

出版信息

J Gen Microbiol. 1988 Jun;134(6):1535-40. doi: 10.1099/00221287-134-6-1535.

Abstract

Two outer-membrane (OM) proteins of Yersinia enterocolitica YOMP-C and YOMP-F appear to function as porins. Mutants that were YOMP-C- and YOMP-F- exhibited changes in cephaloridine and [3H]glucose uptake and increased resistance to beta-lactam antibiotics (especially cephalosporins) and tetracycline. Alterations in OM permeability may contribute to antibiotic resistance in Yersinia.

摘要

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